Immunoglobulin G4-related disease presenting as an intracranial mass extended from the infratemporal fossa.

Kais Maamri, Mohamed Amine Hadj Taieb, Ghassen Elkahla, Rym Hadhri, Mehdi Dermoul

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Article in Surgical neurology international, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed

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0 citing papers in PubMed, 1 citations in OpenAlex.

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5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Kais MaamriDepartment of Neurosurgery Fattouma Bourguiba University Hospital, University of Monastir, Monastir, Tunisia.

Mohamed Amine Hadj TaiebDepartment of Neurosurgery Fattouma Bourguiba University Hospital, University of Monastir, Monastir, Tunisia.

Ghassen ElkahlaDepartment of Neurosurgery Fattouma Bourguiba University Hospital, University of Monastir, Monastir, Tunisia.

Rym HadhriDepartment of Histopathology, Fattouma Bourguiba University Hospital, University of Monastir, Monastir, Tunisia.

Mehdi DermoulDepartment of Neurosurgery Fattouma Bourguiba University Hospital, University of Monastir, Monastir, Tunisia.

Hospital Fatuma Bourguiba Monastir · TN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Neurological manifestations in immunoglobulin G4-related diseases (IgG4-RD) are rare and documented in <2% of cases. It commonly involves pachymeninges forming hypertrophic pachymeningitis and rarely forms tumor-like masses. Case Description: We present our experience with a biopsy-proven case of IgG4-RD presenting with an intracranial extradural tumor-like mass infiltrating the temporal lobe. The patient was treated with high doses of corticosteroids followed by slow tapering. The neurological manifestations gradually improved and resolved after 2 months with a cerebral MRI showing a significant reduction in the tumoral size. Conclusion: When it comes to intracranial mass, IgG4-RD neuropathy is one of the rarest differential diagnoses for the central nervous system tumors. Early recognition of IgG4-RD and appropriate establishment of its long-term treatment may avoid unnecessary investigations and morbidity.

Indexed as

CorticosteroidsExtra-axial neoplasmImmunoglobulin G4-related diseaseNeurological manifestationsPseudo-tumors

Identifiers

PMID35673662

DOI10.25259/SNI_149_2022

PMCPMC9168305

OpenAlexW4281651357

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.