Evidence map›Paper›PMID 35673517›Full record

ArticleJournal of diabetes and metabolic disorders2022

Factors related to barriers and medication adherence in patients with type 2 diabetes mellitus: a cross-sectional study.

Elida Zairina, Gesnita Nugraheni, Arie Sulistyarini, Mufarrihah, Catur Dian Setiawan, Sunil Kripalani, Safira Indah Lestari

Abstract read
In one paragraph

Article in Journal of diabetes and metabolic disorders, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Elida ZairinaDepartment of Pharmacy Practice, Faculty of Pharmacy, Universitas Airlangga, Jl. Dr Ir Haji Soekarno, Mulyorejo, Surabaya, 60115 Indonesia.ORCID 0000-0003-0845-4640
Gesnita NugraheniDepartment of Pharmacy Practice, Faculty of Pharmacy, Universitas Airlangga, Jl. Dr Ir Haji Soekarno, Mulyorejo, Surabaya, 60115 Indonesia.ORCID 0000-0002-8791-8556
Arie SulistyariniDepartment of Pharmacy Practice, Faculty of Pharmacy, Universitas Airlangga, Jl. Dr Ir Haji Soekarno, Mulyorejo, Surabaya, 60115 Indonesia.ORCID 0000-0001-8886-7888
MufarrihahDepartment of Pharmacy Practice, Faculty of Pharmacy, Universitas Airlangga, Jl. Dr Ir Haji Soekarno, Mulyorejo, Surabaya, 60115 Indonesia.ORCID 0000-0002-3043-7671
Catur Dian SetiawanDepartment of Pharmacy Practice, Faculty of Pharmacy, Universitas Airlangga, Jl. Dr Ir Haji Soekarno, Mulyorejo, Surabaya, 60115 Indonesia.ORCID 0000-0002-3642-9947
Sunil KripalaniDepartment of Medicine, Vanderbilt University Medical Center, Nashville, TN USA.ORCID 0000-0002-4214-7129
Safira Indah LestariBachelor of Pharmacy Study Program, Faculty of Pharmacy, Universitas Airlangga, Jl. Dr Ir Haji Soekarno, Mulyorejo, Surabaya, 60115 Indonesia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: Evidence has shown that 50% of patients, including type 2 diabetes mellitus (DM), are non-adherent to the prescribed antidiabetic medication regimen. Some barriers lead to nonadherence in people with DM type 2. The study aimed to identify factors related to adherence in patient with DM and to assess the correlation between barriers to adherence type 2 DM patients. Methods: The cross-sectional study was conducted in 63 primary healthcare centers in Surabaya, Indonesia. Patients with DM type 2 were recruited between April and September 2019 using convenient sampling technique. Ethics approval was obtained (80/EA/KEPK/2019). Results: A total of 266 patients with type 2 DM participated in this study. Of the respondents, 201 (75.2%) were female. Unwanted drug effects, changes in medication regimens, and refilling the prescription when the drugs run out were most reported factors that affected adherence. Spearman correlations and linear regression tests were used to examine the relationship between barriers to medication adherence, and education with medication adherence. A significant difference was observed between the level of education and adherence (p = 0.031). The results showed an association between barriers to medication and adherence to medication (r = 0.304; p < 0.001) which was confirmed in regression analysis (R = 0.309, R square = 0.095, p <0.001). Conclusions: Barriers to adherence are common and affect adherence to therapy. It is essential to expand the roles of health care professionals in the community to include counseling, barrier-monitoring, education, and problem-solving to improve patient medication adherence.

Indexed as

Chronic illnessDiabetes mellitusDrug adherencePatient compliancePrimary care

Identifiers

PMID35673517
PMCPMC9167265

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.