Evidence map›Paper›PMID 35673326›Full record

ReviewStatistical methods & applications2022

Bayesian graphical models for modern biological applications.

Yang Ni, Veerabhadran Baladandayuthapani, Marina Vannucci, Francesco C Stingo

Abstract readReview
In one paragraph

Review in Statistical methods & applications, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Connectivity Regression.Biostatistics (Oxford, England) · 2025
    Article
  6. Article
  7. Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Yang NiDepartment of Statistics, Texas A&M University, College Station, USA.
Veerabhadran BaladandayuthapaniDepartment of Biostatistics, University of Michigan, Ann Arbor, USA.
Marina VannucciDepartment of Statistics, Rice University, Houston, USA.
Francesco C StingoDepartment of Statistics, Computer Science, Applications "G. Parenti", The University of Florence, Florence, Italy.ORCID 0000-0001-9150-8552

Funding

XenograftP30CA046592 · NCI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Alexey I Nesvizhskii · 1988 to 2026
$178.2M
Bayesian Network-Based Integrative Genomics Methods for Precision MedicineR01CA244845 · NCI · UNIVERSITY OF PENNSYLVANIA · PI BALADANDAYUTHAPANI, VEERABHADRAN, MORRIS, JEFFREY S · 2021 to 2024
$1.8M
Integrative methods for high-dimensional genomics dataR01CA160736 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI BALADANDAYUTHAPANI, VEERABHADRAN · 2011 to 2014
$1.4M
Proteomic-based integrated subject-specific networks in cancerR21CA220299 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI BALADANDAYUTHAPANI, VEERABHADRAN, HA, MIN JIN · 2018 to 2019
$378k
NCI NIH HHS P30 CA046592NCI NIH HHS R01 CA160736NCI NIH HHS R01 CA244845NCI NIH HHS R21 CA220299
6 · The paper itself

Abstract

Graphical models are powerful tools that are regularly used to investigate complex dependence structures in high-throughput biomedical datasets. They allow for holistic, systems-level view of the various biological processes, for intuitive and rigorous understanding and interpretations. In the context of large networks, Bayesian approaches are particularly suitable because it encourages sparsity of the graphs, incorporate prior information, and most importantly account for uncertainty in the graph structure. These features are particularly important in applications with limited sample size, including genomics and imaging studies. In this paper, we review several recently developed techniques for the analysis of large networks under non-standard settings, including but not limited to, multiple graphs for data observed from multiple related subgroups, graphical regression approaches used for the analysis of networks that change with covariates, and other complex sampling and structural settings. We also illustrate the practical utility of some of these methods using examples in cancer genomics and neuroimaging.

Indexed as

Bayesian methodsComplex dataGenomicsGraphical modelsNeuroimaging

Identifiers

PMID35673326
PMCPMC9165295

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.