Evidence map›Paper›PMID 35672888›Full record

ArticleJournal of orthopaedic research : official publication of the Orthopaedic Research Society2023

Biomechanical guidance can improve accuracy of reduction for intra-articular tibia plafond fractures and reduce joint contact stress.

Michael C Willey, Andrew M Kern, Jessica E Goetz, John Lawrence Marsh, Donald D Anderson

Open access · hybridAbstract read
In one paragraph

Article in Journal of orthopaedic research : official publication of the Orthopaedic Research Society, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 14 citations in OpenAlex.

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  7. A Novel System for Markerless Intra-Operative Bone and Bone Fragment Tracking.Computer methods in biomechanics and biomedical engineering. Imaging & visualization · 2025
    Article
  8. Article
  9. Persistently elevated joint contact stress after periacetabular osteotomy is associated with joint failure at minimum 10-year follow-up.Journal of orthopaedic research : official publication of the Orthopaedic Research Society · 2024
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Michael C WilleyDepartment of Orthopedics and Rehabilitation, University of Iowa, Iowa City, Iowa, USA.ORCID 0000-0002-6922-8471
Andrew M KernDepartment of Orthopedics and Rehabilitation, University of Iowa, Iowa City, Iowa, USA.
Jessica E GoetzDepartment of Orthopedics and Rehabilitation, University of Iowa, Iowa City, Iowa, USA.ORCID 0000-0002-7197-5978
John Lawrence MarshDepartment of Orthopedics and Rehabilitation, University of Iowa, Iowa City, Iowa, USA.ORCID 0000-0002-3494-6289
Donald D AndersonDepartment of Orthopedics and Rehabilitation, University of Iowa, Iowa City, Iowa, USA.ORCID 0000-0002-1640-6107
University of Iowa · US

Funding

Tissue and Experimental Modeling CoreP50AR055533 · NIAMS · UNIVERSITY OF IOWA · PI GOETZ, JESSICA E · 2007 to 2016
$14.9M
Quantifying Fracture Severity Using a 3-D Puzzle Solving ApproachR21AR054015 · NIAMS · UNIVERSITY OF IOWA · PI ANDERSON, DONALD D · 2008 to 2009
$359k
NIAMS NIH HHS P50 AR055533NIAMS NIH HHS P50AR055533NIAMS NIH HHS R21 AR054015NIAMS NIH HHS R21AR054015
6 · The paper itself

Abstract

Articular fracture malreduction increases posttraumatic osteoarthritis (PTOA) risk by elevating joint contact stress. A new biomechanical guidance system (BGS) that provides intraoperative assessment of articular fracture reduction and joint contact stress based solely on a preoperative computed tomography (CT) and intraoperative fluoroscopy may facilitate better fracture reduction. The objective of this proof-of-concept cadaveric study was to test this premise while characterizing BGS performance. Articular tibia plafond fractures were created in five cadaveric ankles. CT scans were obtained to provide digital models. Indirect reduction was performed in a simulated operating room once with and once without BGS guidance. CT scans after fixation provided models of the reduced ankles for assessing reduction accuracy, joint contact stresses, and BGS accuracy. BGS was utilized 4.8 ± 1.3 (mean ± SD) times per procedure, increasing operative time by 10 min (39%), and the number of fluoroscopy images by 31 (17%). Errors in BGS reduction assessment compared to CT-derived models were 0.45 ± 0.57 mm in translation and 2.0 ± 2.5° in rotation. For the four ankles that were successfully reduced and fixed, associated absolute errors in computed mean and maximum contact stress were 0.40 ± 0.40 and 0.96 ± 1.12 MPa, respectively. BGS reduced mean and maximum contact stress by 1.1 and 2.6 MPa, respectively. BGS thus improved the accuracy of articular fracture reduction and significantly reduced contact stress. Statement of Clinical Significance: Malreduction of articular fractures is known to lead to PTOA. The BGS described in this work has potential to improve quality of articular fracture reduction and clinical outcomes for patients with a tibia plafond fracture.

Indexed as

Ankle FracturesIntra-Articular FracturesOsteoarthritisTibial FracturesCadaverFracture FixationHumansJointsTibiabiomechanical guidancecomputer-assisted surgeryintra-articular fracturepost-traumatic osteoarthritis

Identifiers

PMID35672888
PMCPMC9726992
OpenAlexW4282025002

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.