Observational studyBMC cancer2022
Is treatment in certified cancer centers related to better survival in patients with pancreatic cancer? Evidence from a large German cohort study.
Observational study in BMC cancer, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04334239 (Wirksamkeit Der Versorgung in Onkologischen Zentren), which is not on this map. Cited by 25 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Wirksamkeit Der Versorgung in Onkologischen Zentren
Who cites it
25 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Disparities in survival of hematologic malignancies in the context of social determinants of health: a systematic review.Blood advances · 2023Pooled it
- The projected rise of pancreatic cancer mortality in Italy: forecasts until 2035.Updates in surgery · 2026Article
- Association of Cancer Care Quality Certification With Survival Across Multiple Cancer Types: A Population-Based Cohort Study in Taiwan.International journal of cancer · 2026Article
- Effects of First Time Minimum Volume Regulation on the Surgical Treatment of Lung Cancer in Germany.Cancers · 2026Article
- Does access to quality accreditation improve health? - Patient-level evidence from German cancer care.The European journal of health economics : HEPAC : health economics in prevention and care · 2026Article
- The effects of certification of head and neck cancer centers on the survival of patients with a head and neck cancer.BMC cancer · 2026Article
- Quality of care before and after initial certification at a German certified hereditary breast and ovarian cancer center.Journal of cancer research and clinical oncology · 2025Article
- Comparison of survival in ovarian cancer patients following treatment in certified gynecologic oncology centers and non-certified hospitals: a German retrospective cohort study (WiZen).Journal of ovarian research · 2025Article
- Review
- Article
- An analysis of the distribution of bone and soft tissue sarcoma diagnoses and their disparities in Southwest Germany: a multicenter approach.Frontiers in oncology · 2025Article
- Punching Above Its Weight: A Head-to-Head Comparison of Deepseek-R1 and OpenAI-o1 on Pancreatic Adenocarcinoma-Related Questions.International journal of medical sciences · 2025Article
- Quality-assured treatment in certified cancer center networks in upper Franconia, Germany: a population-centered retrospective cohort analysis based on data of the Bavarian cancer registry.BMC health services research · 2024Article
- Treatment in certified cancer centers is related to better survival in patients with colon and rectal cancer: evidence from a large German cohort study.World journal of surgical oncology · 2024Article
- Adherence to interdisciplinary tumor board recommendations as an expression of quality-assured patient care: results of a bicentric German analysis.Journal of cancer research and clinical oncology · 2023Article
- Development and implementation of a student tumor board as a teaching format for medical students.Journal of cancer research and clinical oncology · 2023Article
- Initial Cancer Treatment in Certified Versus Non-Certified Hospitals.Deutsches Arzteblatt international · 2023Observational
- Assessment of the Potential of Concentrating Cancer Care in Hospitals With Certification Through Survival Analysis.Gesundheitswesen (Bundesverband der Arzte des Offentlichen Gesundheitsdienstes (Germany)) · 2023Article
- Mapping the Oncological Basis Dataset to the Standardized Vocabularies of a Common Data Model: A Feasibility Study.Cancers · 2023Article
- Ten recommendations for sarcoma surgery: consensus of the surgical societies based on the German S3 guideline "Adult Soft Tissue Sarcomas".Langenbeck's archives of surgery · 2023Article
Corrections and comments
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Authors and funding
13 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundTreatment of cancer patients in certified cancer centers, that meet specific quality standards in term of structures and procedures of medical care, is a national treatment goal in Germany. However, convincing evidence that treatment in certified cancer centers is associated with better outcomes in patients with pancreatic cancer is still missing.
methodsWe used patient-specific information (demographic characteristics, diagnoses, treatments) from German statutory health insurance data covering the period 2009-2017 and hospital characteristics from the German Standardized Quality Reports. We investigated differences in survival between patients treated in hospitals with and without pancreatic cancer center certification by the German Cancer Society (GCS) using the Kaplan-Meier estimator and Cox regression with shared frailty.
resultsThe final sample included 45,318 patients with pancreatic cancer treated in 1,051 hospitals (96 GCS-certified, 955 not GCS-certified). 5,426 (12.0%) of the patients were treated in GCS-certified pancreatic cancer centers. Patients treated in certified and non-certified hospitals had similar distributions of age, sex, and comorbidities. Median survival was 8.0 months in GCS-certified pancreatic cancer centers and 4.4 months in non-certified hospitals. Cox regression adjusting for multiple patient and hospital characteristics yielded a significantly lower hazard of long-term, all-cause mortality in patients treated in GCS-certified pancreatic centers (Hazard ratio = 0.89; 95%-CI = 0.85-0.93). This result remained robust in multiple sensitivity analyses, including stratified estimations for subgroups of patients and hospitals.
conclusionThis robust observational evidence suggests that patients with pancreatic cancer benefit from treatment in a certified cancer center in terms of survival. Therefore, the certification of hospitals appears to be a powerful strategy to improve patient outcomes in pancreatic cancer care.
trial registrationClinicalTrials.gov ( NCT04334239 ).
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