Evidence map›Paper›PMID 35672616›Full record

ArticleJournal of autism and developmental disorders2023

Neural Processing of Speech Sounds in ASD and First-Degree Relatives.

Shivani P Patel, Molly Winston, Janna Guilfoyle, Trent Nicol, Gary E Martin, Kritika Nayar, Nina Kraus, Molly Losh

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In one paragraph

Article in Journal of autism and developmental disorders, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
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  5. Article
  6. Article
  7. Rapid FFR: A rapid method for obtaining Frequency Following Responses.bioRxiv : the preprint server for biology · 2025
    Article
  8. Prosodic Differences in Women with theInternational journal of molecular sciences · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Shivani P PatelRoxelyn and Richard Pepper Department of Communication Sciences and Disorders, Northwestern University, 2240 N Campus Dr, Evanston, IL, 60208, USA.
Molly WinstonRoxelyn and Richard Pepper Department of Communication Sciences and Disorders, Northwestern University, 2240 N Campus Dr, Evanston, IL, 60208, USA.
Janna GuilfoyleRoxelyn and Richard Pepper Department of Communication Sciences and Disorders, Northwestern University, 2240 N Campus Dr, Evanston, IL, 60208, USA.
Trent NicolRoxelyn and Richard Pepper Department of Communication Sciences and Disorders, Northwestern University, 2240 N Campus Dr, Evanston, IL, 60208, USA.
Gary E MartinDepartment of Communication Sciences and Disorders, St. John's University, Staten Island, NY, USA.
Kritika NayarRoxelyn and Richard Pepper Department of Communication Sciences and Disorders, Northwestern University, 2240 N Campus Dr, Evanston, IL, 60208, USA.
Nina KrausRoxelyn and Richard Pepper Department of Communication Sciences and Disorders, Northwestern University, 2240 N Campus Dr, Evanston, IL, 60208, USA.
Molly LoshRoxelyn and Richard Pepper Department of Communication Sciences and Disorders, Northwestern University, 2240 N Campus Dr, Evanston, IL, 60208, USA. m-losh@northwestern.edu.ORCID http://orcid.org/0000-0002-9823-8249

Funding

A Family-Genetic Study of Language in AutismR01DC010191 · NIDCD · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Molly C Losh · 2010 to 2026
$7.8M
Research Management & Experimental Tools ResourcesP30DC012035 · NIDCD · NORTHWESTERN UNIVERSITY · PI LARSON, CHARLES R · 2013 to 2017
$2.3M
Novel Computational Analysis of Prosody in ASD and the Broad Autism PhenotypeR03DC018644 · NIDCD · NORTHWESTERN UNIVERSITY · PI LOSH, MOLLY C · 2020 to 2021
$149k
Perception and central coherence in autism: A family genetic eye-tracking studyR03MH107834 · NIMH · NORTHWESTERN UNIVERSITY · PI LOSH, MOLLY C · 2016 to 2017
$147k
NIDCD NIH HHS P30 DC012035NIDCD NIH HHS R01 DC010191NIDCD NIH HHS R03 DC018644NIH HHS P30DC012035NIH HHS R01DC010191NIH HHS R03MH107834NIMH NIH HHS R03 MH107834
6 · The paper itself

Abstract

Efficient neural encoding of sound plays a critical role in speech and language, and when impaired, may have reverberating effects on communication skills. This study investigated disruptions to neural processing of temporal and spectral properties of speech in individuals with ASD and their parents and found evidence of inefficient temporal encoding of speech sounds in both groups. The ASD group further demonstrated less robust neural representation of spectral properties of speech sounds. Associations between neural processing of speech sounds and language-related abilities were evident in both groups. Parent-child associations were also detected in neural pitch processing. Together, results suggest that atypical neural processing of speech sounds is a heritable ingredient contributing to the ASD language phenotype.

Indexed as

Autism Spectrum DisorderSpeech PerceptionHumansLanguagePhoneticsSpeechAutism spectrum disorderBroad autism phenotypeFrequency following responsePragmatic languageProsodySound processing

Identifiers

PMID35672616
PMCPMC10019095

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.