Evidence map›Paper›PMID 35672579›Full record

ArticleInternational orthopaedics2022

Hamstring tendon autografts and allografts show comparable clinical outcomes and knee stability after anterior cruciate ligament reconstruction in patients over fifty years old with no signs of osteoarthritis progression.

Riccardo D'Ambrosi, Riccardo Giorgino, Katia Corona, Tarun Jaykumar, Ilaria Mariani, Nicola Ursino, Laura Mangiavini, Raju Vaishya

Registry-linked trialOpen access · hybridAbstract read
In one paragraph

Article in International orthopaedics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07387939 (Anterior Cruciate Ligament Reconstruction in Patients Aged 50 Years and Older), which is not on this map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
2.4field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07387939 active not recruitingnot on this mapstarted 2024, after this paper: background citation

Anterior Cruciate Ligament Reconstruction in Patients Aged 50 Years and Older

TypeobservationalSponsorI.R.C.C.S Ospedale Galeazzi-Sant'AmbrogioRan2024 to 2026Enrolled56ConditionsACL Injury
3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 13 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Serial change of femoral and tibial tunnel width after anterior cruciate ligament reconstruction with allograft.Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2023
    Article
  4. Review
  5. Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 7 institutions in 2 countries.

Riccardo D'AmbrosiIRCCS Orthopedic Institute Galeazzi, Milan, Italy. riccardo.dambrosi@hotmail.it.
Riccardo GiorginoResidency Program in Orthopedics and Traumatology, University of Milan, 20122, Milan, Italy.
Katia CoronaDepartment of Medicine, Health Sciences "Vincenzo Tiberio," University of Molise, Campobasso, Italy.
Tarun JaykumarSunshine Hospital, Hyderabad, India.
Ilaria MarianiInstitute, for Maternal and Child Health IRCCS Burlo Garofolo, Trieste, Italy.
Nicola UrsinoIRCCS Orthopedic Institute Galeazzi, Milan, Italy.
Laura MangiaviniIRCCS Orthopedic Institute Galeazzi, Milan, Italy.
Raju VaishyaIndraprastha Apollo Hospitals, New Delhi, India.
Istituti di Ricovero e Cura a Carattere Scientifico · ITIndraprastha Apollo Hospitals · INIRCCS Materno Infantile Burlo Garofolo · ITIstituto Ortopedico Galeazzi · ITSunshine Hospitals · INUniversity of Milan · ITUniversity of Molise · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe aim of this study is to compare the functional outcomes and osteoarthritis (OA) progression after anterior cruciate ligament (ACL) reconstruction with either hamstring autografts or allografts in people over 50.

methodsThe clinical records of two consecutive cohorts of 61 cases in total over 50 years of age, undergoing ACL reconstruction, were included. The first cohort consisted of 29 allografts; the second cohort consisted of 32 autologous hamstring tendon grafts. The cases were evaluated pre- (T

resultsNo pre-operative difference was found between the two groups (p > 0.05). No statistical difference was noted between the two groups at each follow-up (p > 0.05). At the final follow-up, both the groups significantly improved statistically in all the clinical and functional scores (p < 0.05). In both groups, one graft re-rupture was noted. No progression of OA was noted in both groups at final follow-up (p > 0.05).

conclusionThe graft choice does not influence the outcomes two years after ACL reconstruction in people over 50; thus, both treatments help in regaining knee stability with no signs of OA progression. REGISTRATION: Researchregistry7539- www.researchregistry.com .

Indexed as

Anterior Cruciate Ligament InjuriesAnterior Cruciate Ligament ReconstructionHamstring TendonsOsteoarthritisAllograftsAutograftsHumansMiddle AgedTransplantation, AutologousTreatment OutcomeACL reconstructionAllograftAutograftHamstringOsteoarthritis progressionOver 50

Identifiers

PMID35672579
PMCPMC9372010
OpenAlexW4281621536

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.