ReviewJournal of neural transmission (Vienna, Austria : 1996)2022
Essential tremor plus rest tremor: current concepts and controversies.
Review in Journal of neural transmission (Vienna, Austria : 1996), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
17 citing papers in PubMed, 30 citations in OpenAlex.
- Olfactory dysfunction in essential tremor with rest tremor: a cross-sectional comparison with parkinson's disease and essential tremor.BMC neurology · 2026Article
- Transcranial static magnetic field stimulation of the primary motor cortex in essential tremor: a randomized pilot study.NPJ Parkinson's disease · 2025Article
- The Relationship between Rest Tremor and Underlying Lewy Pathology in Essential Tremor: A Clinical-Pathological Study of 201 Cases.Annals of neurology · 2025Article
- Unraveling morphological brain network disparities Parkinsonian tremor from essential tremor: an artificial intelligence approach for clinical differentiation.NPJ Parkinson's disease · 2025Article
- Determinants of clinical and neurophysiological features in essential tremor and essential tremor plus.Journal of neural transmission (Vienna, Austria : 1996) · 2025Article
- Striatal Dopaminergic Function and Motor Slowing in Essential Tremor Plus.Movement disorders clinical practice · 2025Article
- Corpus Callosum Structural Alterations in Essential Tremor with and Without Resting Tremor: A Multimodal MRI Study.Tremor and other hyperkinetic movements (New York, N.Y.) · 2025Article
- Clinical Features of Essential Tremor and its Impact on Quality of Life in Japan.Tremor and other hyperkinetic movements (New York, N.Y.) · 2025Article
- Polysomnographic Evaluation of Sleep Disorders in Essential Tremor and Essential Tremor Plus: A Comparison With Healthy Controls.Journal of movement disorders · 2025Article
- Frequency of tremor in people with multiple sclerosis: A systematic review and meta-analysis.Clinical parkinsonism & related disorders · 2025Review
- REM sleep behavior disorder and Prodromal Parkinson's Disease in patients with Essential Tremor.Sleep medicine: X · 2024Article
- Clinical and kinematic characterization of parkinsonian soft signs in essential tremor.Journal of neural transmission (Vienna, Austria : 1996) · 2024Article
- Bedside clinical assessment of patients with common upper limb tremor and algorithmic approach.Asian biomedicine : research, reviews and news · 2024Review
- Combined cortical thickness and blink reflex recovery cycle to differentiate essential tremor with and without resting tremor.Frontiers in neurology · 2024Article
- Testing for Alcohol Responsiveness in Familial Essential Tremor.Tremor and other hyperkinetic movements (New York, N.Y.) · 2024Article
- Cortical involvement in essential tremor with and without rest tremor: a machine learning study.Journal of neurology · 2023Article
- Diagnosis Versus Classification of Essential Tremor: A Research Perspective.Journal of movement disorders · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Since the initial description of Essential Tremor (ET), the entity of ET with rest tremor has proven to be a controversial concept. Some authors argued it could be a late manifestation of ET, others suggested it could be a variant of ET, yet others suggested it could represent a transitional state between ET and Parkinson's disease. The novel tremor classification has proposed the construct of ET-plus to differentiate patients with rest tremor from pure ET. However, there is no clarity of what ET-plus rest tremor represents. With the aim of shedding light on this controversial entity, we have, therefore, systematically reviewed all clinical, electrophysiological, imaging and anatomopathological studies indexed in the Medline database published both before and after the new tremor classification and involving patients with ET-plus rest tremor. Forty-four studies involving 4028 patients were included in this review and analyzed in detail by means of descriptive statistics. The results of the current review suggest that ET-plus rest tremor is a heterogenous group of conditions: thus, rest tremor might represent a late feature of ET, might reflect a different disorder with higher age at onset and lower dependance on genetic susceptibility than ET, might suggest the development of Parkinson's disease or might indicate a misdiagnosis of ET. The reviewed lines of evidence refuse recent claims arguing against the construct of ET-plus, which should be viewed as a syndrome with different possible underpinnings, and highlights methodological issues to be solved in future research.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.