Evidence map›Paper›PMID 35672398›Full record

ArticleNature communications2022

Mafa-dependent GABAergic activity promotes mouse neonatal apneas.

Laure Lecoin, Bowen Dempsey, Alexandra Garancher, Steeve Bourane, Pierre-Louis Ruffault, Marie-Pierre Morin-Surun, Nathalie Rocques, Martyn Goulding, Alain Eychène, Celio Pouponnot and 2 more

Open access · goldAbstract read
In one paragraph

Article in Nature communications, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 51% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 4 countries.

Laure LecoinInstitut Curie CNRS UMR 3347, Inserm U1021, UPSaclay, bat 110 Centre Universitaire, 91405, ORSAY, France. laure.lecoin@college-de-france.fr.ORCID 0000-0001-5259-4339
Bowen DempseyUMR 9194 CNRS Neuro-PSI, Institut de Neurobiologie Alfred Fessard, 1 avenue de la terrasse, 91190, Gif-sur-Yvette, France.
Alexandra GarancherInstitut Curie CNRS UMR 3347, Inserm U1021, UPSaclay, bat 110 Centre Universitaire, 91405, ORSAY, France.ORCID 0000-0001-5779-2860
Steeve BouraneMolecular Neurobiology Laboratory, The Salk Institute for Biological Studies, La Jolla, CA, 92037, USA.ORCID 0000-0002-9805-2196
Pierre-Louis RuffaultDevelopmental Biology and Signal Transduction Group, Max Delbrück Center for Molecular Medicine, 13125, Berlin, Germany.
Marie-Pierre Morin-SurunUMR 9194 CNRS Neuro-PSI, Institut de Neurobiologie Alfred Fessard, 1 avenue de la terrasse, 91190, Gif-sur-Yvette, France.
Nathalie RocquesInstitut Curie CNRS UMR 3347, Inserm U1021, UPSaclay, bat 110 Centre Universitaire, 91405, ORSAY, France.
Martyn GouldingMolecular Neurobiology Laboratory, The Salk Institute for Biological Studies, La Jolla, CA, 92037, USA.
Alain EychèneInstitut Curie CNRS UMR 3347, Inserm U1021, UPSaclay, bat 110 Centre Universitaire, 91405, ORSAY, France.ORCID 0000-0002-6818-7225
Celio PouponnotInstitut Curie CNRS UMR 3347, Inserm U1021, UPSaclay, bat 110 Centre Universitaire, 91405, ORSAY, France. celio.pouponnot@curie.fr.ORCID 0000-0002-9795-0496
Gilles FortinUMR 9194 CNRS Neuro-PSI, Institut de Neurobiologie Alfred Fessard, 1 avenue de la terrasse, 91190, Gif-sur-Yvette, France. gilles.fortin@bio.ens.psl.eu.ORCID 0000-0002-2123-8603
Jean ChampagnatUMR 9194 CNRS Neuro-PSI, Institut de Neurobiologie Alfred Fessard, 1 avenue de la terrasse, 91190, Gif-sur-Yvette, France.
Centre National de la Recherche Scientifique · FRSalk Institute for Biological Studies · USMax Delbrück Center · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

While apneas are associated with multiple pathological and fatal conditions, the underlying molecular mechanisms remain elusive. We report that a mutated form of the transcription factor Mafa (Mafa

Indexed as

ApneaMotor NeuronsAnimalsMaf Transcription Factors, LargeMicePhosphorylationPromoter Regions, GeneticMafa protein, mouseMaf Transcription Factors, Large

Identifiers

PMID35672398
PMCPMC9174494
OpenAlexW4281722796

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.