ArticleNature communications2022
Switching the NIR upconversion of nanoparticles for the orthogonal activation of photoacoustic imaging and phototherapy.
Article in Nature communications, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
What it found
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Who cites it
21 citing papers in PubMed.
- Bioorthogonal Photoactivation of 2-Nitrobenzyl Caged Doxorubicin Anticancer Prodrugs on Gold Nanostars.Advanced materials (Deerfield Beach, Fla.) · 2026Article
- Tailoring Photonic Landscape: Nanoengineering Empowers NIR-II Lanthanide Luminescence for Versatile Biomedical Applications.Small methods · 2026Review
- Harnessing Rare-Earth Materials as Exogenous Contrast Agents for Enhanced Photoacoustic Imaging.Chemical & biomedical imaging · 2026Review
- Activatable smart contrast agents for photoacoustic imaging.Smart molecules : open access · 2026Review
- Advances in Photonic Materials and Integrated Devices for Smart and Digital Healthcare: Bridging the Gap Between Materials and Systems.Advanced materials (Deerfield Beach, Fla.) · 2025Review
- Upconversion Nanoparticle-Covalent Organic Framework Core-shell Particles as Therapeutic Microrobots Trackable With Optoacoustic Imaging.Advanced materials (Deerfield Beach, Fla.) · 2025Article
- Amplifying Anti-Tumor Immune Responses via Mitochondria-Targeting Near-Infrared Photodynamic Therapy.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Article
- Multifunctional Upconversion Nanoparticles Transforming Photoacoustic Imaging: A Review.Nanomaterials (Basel, Switzerland) · 2025Review
- Noninvasive cardiac modulation via triplet-sensitized photoswitching in the phototherapeutic window.Nature communications · 2025Article
- Full-color tuning in multi-layer core-shell nanoparticles from single-wavelength excitation.Nature communications · 2025Article
- A self-assembling nanoplatform for pyroptosis and ferroptosis enhanced cancer photoimmunotherapy.Light, science & applications · 2025Article
- Bioimaging and prospects of night pearls-based persistence phosphors in cancer diagnostics.Exploration (Beijing, China) · 2024Review
- Sonosynthetic Cyanobacteria Oxygenation for Self-Enhanced Tumor-Specific Treatment.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024Article
- Programmable "triple attack" cancer therapy throughChemical science · 2024Article
- Comparison of the Differences between Two-Photon Excitation, Upconversion, and Conventional Photodynamic Therapy on Cancers in In Vitro and In Vivo Studies.Pharmaceuticals (Basel, Switzerland) · 2024Review
- Spatiotemporal control of photochromic upconversion through interfacial energy transfer.Nature communications · 2024Article
- Photonic control of image-guided ferroptosis cancer nanomedicine.Coordination chemistry reviews · 2024Article
- Hollow mesoporous organosilica nanoparticles reduced graphene oxide based nanosystem for multimodal image-guided photothermal/photodynamic/chemo combinational therapy triggered by near-infrared.Cell proliferation · 2023Article
- Integration of AIEgens into covalent organic frameworks for pyroptosis and ferroptosis primed cancer immunotherapy.Nature communications · 2023Article
- Full-view LED-based optoacoustic tomography.Photoacoustics · 2023Article
Corrections and comments
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Phototheranostics based on upconversion nanoparticles (UCNPs) offer the integration of imaging diagnostics and phototherapeutics. However, the programmable control of the photoactivation of imaging and therapy with minimum side effects is challenging due to the lack of ideal switchable UCNPs agents. Here we demonstrate a facile strategy to switch the near infrared emission at 800 nm from rationally designed UCNPs by modulating the irradiation laser into pulse output. We further synthesize a theranostic nanoagent by combining with a photosensitizer and a photoabsorbing agent assembled on the UCNPs. The orthogonal activation of in vivo photoacoustic imaging and photodynamic therapy can be achieved by altering the excitation modes from pulse to continuous-wave output upon a single 980 nm laser. No obvious harmful effects during photoexcitation was identified, suggesting their use for long-term imaging-guidance and phototherapy. This work provides an approach to the orthogonal activation of imaging diagnostics and photodynamic therapeutics.
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