Evidence map›Paper›PMID 35671268›Full record

ArticlePloS one2022

Mechanical nociceptive assessment of the equine hoof after navicular bursa anesthetic infiltration validated by bursography.

Letícia de Oliveira Cota, Bruno Dondoni Malacarne, Lucas Antunes Dias, Antônio Catunda Pinho Neto, Maria Luiza Arruda Kneipp, Marina Alcântara Cavalcante, Marina de Souza Luz da Cunha, Cahuê Francisco Rosa Paz, Armando de Mattos Carvalho, Rafael Resende Faleiros and 1 more

Open access · goldAbstract read
In one paragraph

Article in PloS one, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 94% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 1 institution in 1 country.

Letícia de Oliveira CotaDepartment Veterinary Clinic and Surgery, EQUINOVA Research Group, Veterinary School, Universidade Federal de Minas Gerais, Belo Horizonte, Minas Gerais, Brazil.ORCID 0000-0002-1328-6998
Bruno Dondoni MalacarneDepartment Veterinary Clinic and Surgery, EQUINOVA Research Group, Veterinary School, Universidade Federal de Minas Gerais, Belo Horizonte, Minas Gerais, Brazil.ORCID 0000-0003-3860-7310
Lucas Antunes DiasDepartment Veterinary Clinic and Surgery, EQUINOVA Research Group, Veterinary School, Universidade Federal de Minas Gerais, Belo Horizonte, Minas Gerais, Brazil.ORCID 0000-0002-7240-6785
Antônio Catunda Pinho NetoDepartment Veterinary Clinic and Surgery, EQUINOVA Research Group, Veterinary School, Universidade Federal de Minas Gerais, Belo Horizonte, Minas Gerais, Brazil.
Maria Luiza Arruda KneippDepartment Veterinary Clinic and Surgery, EQUINOVA Research Group, Veterinary School, Universidade Federal de Minas Gerais, Belo Horizonte, Minas Gerais, Brazil.ORCID 0000-0003-1311-064X
Marina Alcântara CavalcanteDepartment Veterinary Clinic and Surgery, EQUINOVA Research Group, Veterinary School, Universidade Federal de Minas Gerais, Belo Horizonte, Minas Gerais, Brazil.
Marina de Souza Luz da CunhaDepartment Veterinary Clinic and Surgery, EQUINOVA Research Group, Veterinary School, Universidade Federal de Minas Gerais, Belo Horizonte, Minas Gerais, Brazil.
Cahuê Francisco Rosa PazDepartment Veterinary Clinic and Surgery, EQUINOVA Research Group, Veterinary School, Universidade Federal de Minas Gerais, Belo Horizonte, Minas Gerais, Brazil.ORCID 0000-0003-2076-3737
Armando de Mattos CarvalhoDepartment Veterinary Clinic and Surgery, EQUINOVA Research Group, Veterinary School, Universidade Federal de Minas Gerais, Belo Horizonte, Minas Gerais, Brazil.
Rafael Resende FaleirosDepartment Veterinary Clinic and Surgery, EQUINOVA Research Group, Veterinary School, Universidade Federal de Minas Gerais, Belo Horizonte, Minas Gerais, Brazil.
Andressa Batista da Silveira XavierDepartment Veterinary Clinic and Surgery, EQUINOVA Research Group, Veterinary School, Universidade Federal de Minas Gerais, Belo Horizonte, Minas Gerais, Brazil.ORCID 0000-0003-1065-6778
Universidade Federal de Minas Gerais · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The analgesic specificity of navicular bursa (NB) anesthetic infiltration is still questionable. The study aimed to determine the mechanical nociceptive threshold of non-specific analgesia in the dorsal lamellar stratum, as well as in the sole, coronary band, and heel bulbs of the hoof, after navicular bursa anesthetic infiltration. Six healthy horses with no clinical or radiographic changes of the digits and no communication between the NB and the distal interphalangeal joint, were used. After random selection, the NB of one of the forelimbs was infiltrated with 2% lidocaine and the contralateral one with lactated ringer's solution. Contrast was added to confirm radiographic infiltration. The mechanical nociceptive threshold was determined using a portable pressure dynamometer, before and at various times after the infiltration, in 10 points of the hoof. The effects of time and treatment were verified by ANOVA (P<0.05). There was no statistical difference in the values of the mechanical nociceptive threshold (P>0.05) in all regions evaluated. However, in one of the six hooves that receives lidocaine, complete absence of response to the painful stimulus (maximum force of 6 Kg over an area of 38.46 mm2, for a maximum of 4 seconds) was observed in the dorsal lamellae between 30 and 60 min after infiltration. In conclusion, lidocaine infiltration of NB did not promote significant increases in the nociceptive threshold of the sole, coronary band, bulbs of the heel and dorsal lamellae clinically healthy horses. However, the occurrence of analgesia in one of the six hooves subjected to NB anesthesia indicates that the technique may not be fully specific in few horses.

Indexed as

Hoof and ClawHorse DiseasesAnesthetics, LocalAnimalsBursa, SynovialForelimbHorsesLidocaineNociceptionPainAnesthetics, LocalLidocaine

Identifiers

PMID35671268
PMCPMC9173607
OpenAlexW4281852247

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.