Evidence map›Paper›PMID 35671222›Full record

ArticleMicrobiology (Reading, England)2022

Lactobacilli and human dental caries: more than mechanical retention.

Zezhang T Wen, Xiaochang Huang, Kassapa Ellepola, Sumei Liao, Yihong Li

Open access · hybridAbstract read
In one paragraph

Article in Microbiology (Reading, England), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
43citing papers in PubMed, 2 pooled it
7.3field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

43 citing papers in PubMed, 2 syntheses or guidelines pooled it, 52 citations in OpenAlex.

  1. Unveiling the dual nature ofFrontiers in oral health · 2025
    Pooled it
  2. Pooled it
  3. Review
  4. Article
  5. Erosive Potential of Commercially Available Cannabis Beverages.Clinical and experimental dental research · 2026
    Article
  6. Article
  7. Review
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  9. Article
  10. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

Zezhang T WenDepartment of Prosthodontics, School of Dentistry and Department of Microbiology, Immunology and Parasitology, School of Medicine, Louisiana State University Health Sciences Center, New Orleans, LA, USA.
Xiaochang HuangDepartment of Prosthodontics, School of Dentistry and Department of Microbiology, Immunology and Parasitology, School of Medicine, Louisiana State University Health Sciences Center, New Orleans, LA, USA.
Kassapa EllepolaDepartment of Prosthodontics, School of Dentistry and Department of Microbiology, Immunology and Parasitology, School of Medicine, Louisiana State University Health Sciences Center, New Orleans, LA, USA.
Sumei LiaoDepartment of Prosthodontics, School of Dentistry and Department of Microbiology, Immunology and Parasitology, School of Medicine, Louisiana State University Health Sciences Center, New Orleans, LA, USA.
Yihong LiDepartment of Public and Ecosystem Health, College of Veterinary Medicine, Cornel University, Ithaca, NY, USA.
Louisiana State University Health Sciences Center New Orleans · USNanchang University · CNUniversity of Illinois Chicago · US

Funding

BrpA in Virulence Modulation of Streptococcus mutansR01DE019452 · NIDCR · LSU HEALTH SCIENCES CENTER · PI ZEZHANG TOM WEN, Hui Wu · 2009 to 2026
$6.3M
eDNA Secretion and eDNA-Cell Interactions in Biofilm FormationR21DE025348 · NIDCR · LSU HEALTH SCIENCES CENTER · PI BRADY, L. JEANNINE, WEN, ZEZHANG TOM · 2016 to 2017
$419k
NIDCR NIH HHS R01 DE019452NIDCR NIH HHS R21 DE025348
6 · The paper itself

Abstract

Lactobacilli have been considered as major contributors to human dental caries for over a century. Recent

Indexed as

BacteriocinsDental CariesBiofilmsHumansLactobacillusStreptococcus mutansBacteriocinsbiofilm formationdental cariesgenetic regulationlactobacillusoral microecologyStreptococcus mutans

Identifiers

PMID35671222
PMCPMC10233465
OpenAlexW4281867315

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.