Evidence map›Paper›PMID 35671134›Full record

ArticleOtolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery2023

Effects of Varying Laser Parameters During Laser Stapedotomy on Intracochlear Pressures.

Elizabeth F Boscoe, Renee M Banakis Hartl, Samuel P Gubbels, Nathaniel T Greene

Open access · greenAbstract read
In one paragraph

Article in Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 52% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Improved Bone Conduction and Hearing Outcomes After Stapes Surgery for Otosclerosis.World journal of otorhinolaryngology - head and neck surgery · 2026
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Elizabeth F BoscoeDepartment of Otolaryngology-Head and Neck Surgery, University of Colorado, Aurora, Colorado, USA.
Renee M Banakis HartlDepartment of Otolaryngology-Head and Neck Surgery, University of Colorado, Aurora, Colorado, USA.
Samuel P GubbelsDepartment of Otolaryngology-Head and Neck Surgery, University of Colorado, Aurora, Colorado, USA.
Nathaniel T GreeneDepartment of Otolaryngology-Head and Neck Surgery, University of Colorado, Aurora, Colorado, USA.
University of Colorado Denver · USUniversity of Michigan–Ann Arbor · US

Funding

Constraints on binaural sensitivity via bilateral bone conductionR21DC017213 · NIDCD · UNIVERSITY OF WASHINGTON · PI BROWN, ANDREW DENNIS · 2019 to 2021
$480k
Improving an animal model of human hearing loss: quantifying risks associated with common otolaryngology proceduresR21DC017809 · NIDCD · UNIVERSITY OF COLORADO DENVER · PI GREENE, NATHANIEL TUSSING · 2019 to 2021
$467k
NIDCD NIH HHS R21 DC017213NIDCD NIH HHS R21 DC017809
6 · The paper itself

Abstract

objectiveSensorineural hearing loss is a known complication of stapes surgery. We previously showed that laser stapedotomy can result in intracochlear pressures that are comparable to high sound pressure levels. Optimizing laser settings to those that correspond with the lowest pressure changes may mitigate risk for postoperative hearing loss. Here we quantify the effects of various laser parameters on intracochlear pressures and test the hypothesis that intracochlear pressure changes are proportional to the laser energy delivered. STUDY

designBasic and translational science.

settingCadaveric dissection and basic science laboratory.

methodsCadaveric human heads underwent mastoidectomies. Intracochlear pressures were measured via fiber-optic pressure probes placed in scala vestibuli and tympani. Pulses of varied stimulus power and duration from a 980-nm diode laser were applied to the stapes footplate.

resultsSustained high-intensity pressures were observed in the cochlea during all laser applications. Observed pressure magnitudes increased monotonically with laser energy and rose linearly for lower stimulus durations and powers, but there was increased variability for laser applications of longer duration (200-300 ms) and/or higher power (8 W).

conclusionsResults confirm that significant pressure changes occur during laser stapedotomy, which we hypothesize may cause injury. Overall energy delivered depends predictably on duration and power, but surgeons should use caution at the highest stimulus levels and longest pulse durations due to the increasing variability in intracochlear pressure under these stimulus conditions. While the risk to hearing from increased intracochlear pressures from laser stapedotomy remains unclear, these results affirm the need to optimize laser settings to avoid unintended injury.

Indexed as

Laser TherapyStapes SurgeryCadaverCochleaHearingHumansLasersintracochlear pressurelasernoise-induced hearing lossstapedectomystapedotomy

Identifiers

PMID35671134
PMCPMC10097413
OpenAlexW4281624742

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.