Evidence map›Paper›PMID 35670957›Full record

ArticleJournal of physiology and biochemistry2022

Intestinal serotonergic system is modulated by Toll-like receptor 9.

Elena Layunta, Eva Latorre, Laura Grasa, María Pilar Arruebo, Berta Buey, Ana I Alcalde, José E Mesonero

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of physiology and biochemistry, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Elena LayuntaInstitute of Biomedicine, Department of Medical Biochemistry and Cell Biology, University of Gothenburg, Gothenburg, Sweden.
Eva LatorreInstituto de Investigación Sanitaria de Aragón (IIS Aragón), Zaragoza, Spain. evalatorre@unizar.es.ORCID http://orcid.org/0000-0002-5797-3909
Laura GrasaInstituto de Investigación Sanitaria de Aragón (IIS Aragón), Zaragoza, Spain.
María Pilar ArrueboInstituto de Investigación Sanitaria de Aragón (IIS Aragón), Zaragoza, Spain.
Berta BueyDepartamento de Farmacología, Fisiología y Medicina Legal y Forense, Facultad de Veterinaria, Universidad de Zaragoza, Zaragoza, Spain.
Ana I AlcaldeDepartamento de Farmacología, Fisiología y Medicina Legal y Forense, Facultad de Veterinaria, Universidad de Zaragoza, Zaragoza, Spain.
José E MesoneroInstituto de Investigación Sanitaria de Aragón (IIS Aragón), Zaragoza, Spain.
Universidad de Zaragoza · ESInstituto de Investigación Sanitaria Aragón · ES

Funding

Foundation for the Study of Inflammatory Bowel Diseases in Aragón ARAINF 012/2008Gobierno de Aragon B61Gobierno de Aragón B022/13Ministerio de Ciencia, Innovación y Universidades BFU2010-18971
6 · The paper itself

Abstract

Intestinal serotonergic system is a key modulator of intestinal homeostasis; however, its regulation is still unclear. Toll-like receptor 9 (TLR9), an innate immune receptor, detects different external agents in the intestine, preserving intestinal integrity. Since little is known about TLR9 role in the intestine, our aim was to address the potential regulation between TLR9 and intestinal serotonergic system. Caco-2/TC7 cell line and intestinal tract of Tlr9

Indexed as

Serotonin Plasma Membrane Transport ProteinsAnimalsCaco-2 CellsHumansIntestinesMiceSerotoninToll-Like Receptor 9SerotoninSerotonin Plasma Membrane Transport ProteinsTLR9 protein, humanTlr9 protein, mouseToll-Like Receptor 9IntestineMicrobiotaPRRsSerotoninSERTTPH

Identifiers

PMID35670957
PMCPMC9381617
OpenAlexW4281623996

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.