Evidence map›Paper›PMID 35670862›Full record

ArticleDiscover oncology2022

Apigenin impedes cell cycle progression at G

Su Su Thae Hnit, Mu Yao, Chanlu Xie, Ling Bi, Matthew Wong, Tao Liu, Paul De Souza, Zhong Li, Qihan Dong

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Discover oncology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
2.8field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 16 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Frontiers in nutrition · 2025
    Review
  5. Review
  6. Article
  7. Review
  8. Review
  9. Phytochemicals in Cancer Chemoprevention: Preclinical and Clinical Studies.Cancer control : journal of the Moffitt Cancer Center
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 6 institutions in 2 countries.

Su Su Thae HnitChinese Medicine Anti-cancer Evaluation Program, Greg Brown Laboratory, Central Clinical School and Charles Perkins Centre, The University of Sydney, Sydney, NSW, Australia.
Mu YaoChinese Medicine Anti-cancer Evaluation Program, Greg Brown Laboratory, Central Clinical School and Charles Perkins Centre, The University of Sydney, Sydney, NSW, Australia.
Chanlu XieChinese Medicine Anti-cancer Evaluation Program, Greg Brown Laboratory, Central Clinical School and Charles Perkins Centre, The University of Sydney, Sydney, NSW, Australia.
Ling BiDepartment of Oncology, Yueyang Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai, China.
Matthew WongChildren's Cancer Institute Australia for Medical Research, Sydney, NSW, Australia.
Tao LiuChildren's Cancer Institute Australia for Medical Research, Sydney, NSW, Australia.
Paul De SouzaSchool of Medicine, Western Sydney University, Sydney , Australia.
Zhong LiDongzhimen Hospital, Beijing University of Chinese Medicine, Beijing, China. lizhong@bucm.edu.cn.
Qihan DongChinese Medicine Anti-cancer Evaluation Program, Greg Brown Laboratory, Central Clinical School and Charles Perkins Centre, The University of Sydney, Sydney, NSW, Australia. Qihan.Dong@sydney.edu.au.
Royal Prince Alfred Hospital · AUChildren's Cancer Institute Australia · AUDongzhimen Hospital Affiliated to Beijing University of Chinese Medicine · CNShanghai University of Traditional Chinese Medicine · CNUniversity of Sydney · AUWestern Sydney University · AU

Funding

National Natural Science Foundation of China 81904163Shanghai Sailing Program 19YF1450000Sydney Medical School Foundation QD
6 · The paper itself

Abstract

As a natural flavone, apigenin is abundantly present in vegetables, fruits, oregano, tea, chamomile, wheat sprout and is regarded as a major component of the Mediterranean diet. Apigenin is known to inhibit proliferation in different cancer cell lines by inducing G

Indexed as

ApigeninG2 phasePhospho-histone H3Prostate

Identifiers

PMID35670862
PMCPMC9174405
OpenAlexW4281755239

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.