Evidence map›Paper›PMID 35670534›Full record

ArticlemSystems2022

Dietary Exposure to Antibiotic Residues Facilitates Metabolic Disorder by Altering the Gut Microbiota and Bile Acid Composition.

Rou-An Chen, Wei-Kai Wu, Suraphan Panyod, Po-Yu Liu, Hsiao-Li Chuang, Yi-Hsun Chen, Qiang Lyu, Hsiu-Ching Hsu, Tzu-Lung Lin, Ting-Chin David Shen and 10 more

Open access · goldAbstract read
In one paragraph

Article in mSystems, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
2.8field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 34 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Microorganisms · 2025
    Review
  5. Review
  6. Review
  7. Article
  8. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors at 6 institutions in 2 countries.

Rou-An Chen *Institute of Food Science and Technology, National Taiwan Universitygrid.19188.39grid.412094.a, Taipei, Taiwan.
Wei-Kai Wu *Department of Medical Research, National Taiwan Universitygrid.19188.39grid.412094.a Hospital, Taipei, Taiwan.
Suraphan PanyodInstitute of Food Science and Technology, National Taiwan Universitygrid.19188.39grid.412094.a, Taipei, Taiwan.
Po-Yu LiuDepartment of Internal Medicine, College of Medicine, National Taiwan Universitygrid.19188.39grid.412094.a, Taipei, Taiwan.ORCID 0000-0003-1290-0850
Hsiao-Li ChuangNational Laboratory Animal Center, National Applied Research Laboratories, Taipei, Taiwan.
Yi-Hsun ChenDepartment of Internal Medicine, College of Medicine, National Taiwan Universitygrid.19188.39grid.412094.a, Taipei, Taiwan.
Qiang LyuDepartment of Chemistry, National Taiwan Universitygrid.19188.39grid.412094.a, Taipei, Taiwan.
Hsiu-Ching HsuThe Metabolomics Core Laboratory, Center of Genomic Medicine, National Taiwan Universitygrid.19188.39grid.412094.a, Taipei, Taiwan.
Tzu-Lung LinDepartment of Medical Biotechnology and Laboratory Science, College of Medicine, Chang Gung University, Taoyuan, Taiwan.
Ting-Chin David ShenDivision of Gastroenterology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Yu-Tang YangDepartment of Internal Medicine, College of Medicine, National Taiwan Universitygrid.19188.39grid.412094.a, Taipei, Taiwan.
Hsin-Bai ZouDepartment of Chemistry, National Taiwan Universitygrid.19188.39grid.412094.a, Taipei, Taiwan.
Huai-Syuan HuangInstitute of Food Science and Technology, National Taiwan Universitygrid.19188.39grid.412094.a, Taipei, Taiwan.
Yu-En LinInstitute of Food Science and Technology, National Taiwan Universitygrid.19188.39grid.412094.a, Taipei, Taiwan.
Chieh-Chang ChenDepartment of Internal Medicine, National Taiwan Universitygrid.19188.39grid.412094.a Hospital, Taipei, Taiwan.
Chi-Tang HoDepartment of Food Science, Rutgers University, New Brunswick, New Jersey, USA.
Hsin-Chih LaiDepartment of Medical Biotechnology and Laboratory Science, College of Medicine, Chang Gung University, Taoyuan, Taiwan.
Ming-Shiang WuDepartment of Internal Medicine, College of Medicine, National Taiwan Universitygrid.19188.39grid.412094.a, Taipei, Taiwan.
Cheng-Chih HsuDepartment of Chemistry, National Taiwan Universitygrid.19188.39grid.412094.a, Taipei, Taiwan.
Lee-Yan SheenInstitute of Food Science and Technology, National Taiwan Universitygrid.19188.39grid.412094.a, Taipei, Taiwan.
National Taiwan University · TWChang Gung University · TWNational Taiwan University Hospital · TWNational Institutes of Applied Research · TWRutgers, The State University of New Jersey · USUniversity of Pennsylvania · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Antibiotics used as growth promoters in livestock and animal husbandry can be detected in animal-derived food. Epidemiological studies have indicated that exposure to these antibiotic residues in food may be associated with childhood obesity. Herein, the effect of exposure to a residual dose of tylosin-an antibiotic growth promoter-on host metabolism and gut microbiota was explored

Indexed as

Gastrointestinal MicrobiomeInsulin ResistancePediatric ObesityAnimalsAnti-Bacterial AgentsBile Acids and SaltsDietary ExposureMiceTylosinAnti-Bacterial AgentsBile Acids and SaltsTylosinbile acid metabolismdietary exposureearly lifefood safetygut microbiotalow-dose antibioticmetabolic disorderobesity

Identifiers

PMID35670534
PMCPMC9239188
OpenAlexW4281729028

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.