ArticleReviews on recent clinical trials2022
Value of Rox Index to Predict Intubation and Intensive Care Unit Outcome in Patients with Respiratory Failure.
Article in Reviews on recent clinical trials, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed, 2 citations in OpenAlex.
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundRecent literature suggests that the respiratory rate oxygenation (ROX) index may be useful in predicting intubation indication in hypoxemic patients.
objectiveIn this study, we evaluated the accuracy of the ROX index in predicting intubation, length of stay in the ICU, and mortality in ICU patients with hypoxemic respiratory failure with and without hypercapnia.
methodsA single-centre retrospective cohort study of 290 patients with a preliminary diagnosis of respiratory failure were treated with low-flow oxygen systems. Demographics, medical history, clinical, laboratory, treatment, and prognostic data were obtained from the hospital's electronic records. The ROX index was calculated at the time of ICU admission.
resultsThirty-seven percent of non-hypercapnic and 69% of hypercapnic patients were intubated (p:0.005). In hypercapnic patients, ROX: 6.9 had highest sensitivity (81%) and specificity (65%) values for intubation (p:0.005). In non-hypercapnic patients, ROX: 6.2 had the highest sensitivity (81%) and specificity (40%) values. While 11% of hypercapnic patients and 30% of non-hypercapnic patients died (p:0.05), 22% of hypercapnic patients and 33% of non-hypercapnic patients stayed in the ICU longer than 14 days (p:0.044). The highest sensitivity and specificity values were found for mortality in hypercapnic patients; for ROX value of 5.94 (sensitivity:86%, specificity:61%) and ICU stay longer than 14 days; for ROX value of 7.4 (sensitivity:71%, specificity:68%).
conclusionResults of our study suggest that the ROX index calculated during ICU admission can help predict intubation indication and length of ICU stay in patients with respiratory failure and hypercapnia may influence the cutoff values.
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