ArticleAdvanced science (Weinheim, Baden-Wurttemberg, Germany)2022
SERS Hotspot Engineering by Aerosol Self-Assembly of Plasmonic Ag Nanoaggregates with Tunable Interparticle Distance.
Article in Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
20 citing papers in PubMed.
- Scalable Fabrication of Highly Ordered Au/Ag Composite Nanoshell Array for Ultrasensitive SERS Detection of Trace Pesticides.Nanomaterials (Basel, Switzerland) · 2026Article
- Imaging strategies for delineating glioma margins: Aiming at precise therapy.Fundamental research · 2026Review
- Plasmonic and surface-enhanced Raman nanobiosensors for quantitative molecular detection.Discover nano · 2026Review
- Early diagnosis of pancreatic ductal adenocarcinoma by signal-enhanced lateral flow immunoassay: SELFI.Nature communications · 2026Article
- From nanotags to precision biomedicine: SERS-driven progress and innovation in tumor biomarker profiling, dynamic bioimaging, AI-enhanced diagnostics and therapy.Theranostics · 2026Review
- Recent Advances in Reactive Microdroplets for Clean Water and Energy.Advanced materials (Deerfield Beach, Fla.) · 2025Review
- Ag Nanocrystals Intercalated Muscovite Mesocrystal for Large-Scale 3D SERS.Nano letters · 2025Article
- Helicobacter pylori Detection Based on Synergistic Electromagnetic and Chemical Enhancement of Surface-Enhanced Raman Scattering in 3D Hotspot-Activated Gold Nanorods/Nano Mica Platelets/ZnO Quantum Dots.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Article
- Thermoplasmonic Nano-Hybrid Core@Shell Ag@SiONanomaterials (Basel, Switzerland) · 2025Article
- Fabricating a Three-Dimensional Surface-Enhanced Raman Scattering Substrate Using Hydrogel-Loaded Freeze-Induced Silver Nanoparticle Aggregates for the Highly Sensitive Detection of Organic Pollutants in Seawater.Sensors (Basel, Switzerland) · 2025Article
- Microfluidic biosensors for biomarker detection in body fluids: a key approach for early cancer diagnosis.Biomarker research · 2024Review
- Flexible paper-based Ag dendritic SERS chips for rapidRSC advances · 2024Article
- Silver/gold nanoalloy implant coatings with antibiofilm activityChemical communications (Cambridge, England) · 2024Article
- Detection of surface enhanced Raman scattering active hotspot using near field scanning optical microscopy.Scientific reports · 2024Article
- Micro-nano hierarchical urchin-like ZnO/Ag hollow sphere for SERS detection and photodegradation of antibiotics.Nanophotonics (Berlin, Germany) · 2024Article
- Flexible Substrate of Cellulose Fiber/Structured Plasmonic Silver Nanoparticles Applied for Label-Free SERS Detection of Malathion.Materials (Basel, Switzerland) · 2023Article
- Highly Efficient Near-IR Photothermal Microneedles with Flame-Made Plasmonic Nanoaggregates for Reduced Intradermal Nanoparticle Deposition.Advanced materials interfaces · 2022Article
- A Novel Bio-Inspired Ag/3D-TiONanomaterials (Basel, Switzerland) · 2022Article
- Nanosensor Applications in Plant Science.Biosensors · 2022Review
- SERS Hotspot Engineering by Aerosol Self-Assembly of Plasmonic Ag Nanoaggregates with Tunable Interparticle Distance.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2022Article
Corrections and comments
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Authors and funding
5 authors.
Funding
Abstract
Surface-enhanced Raman scattering (SERS) is a powerful sensing technique. However, the employment of SERS sensors in practical applications is hindered by high fabrication costs from processes with limited scalability, poor batch-to-batch reproducibility, substrate stability, and uniformity. Here, highly scalable and reproducible flame aerosol technology is employed to rapidly self-assemble uniform SERS sensing films. Plasmonic Ag nanoparticles are deposited on substrates as nanoaggregates with fine control of their interparticle distance. The interparticle distance is tuned by adding a dielectric spacer during nanoparticle synthesis that separates the individual Ag nanoparticles within each nanoaggregate. The dielectric spacer thickness dictates the plasmonic coupling extinction of the deposited nanoaggregates and finely tunes the Raman hotspots. By systematically studying the optical and morphological properties of the developed SERS surfaces, structure-performance relationships are established and the optimal hot-spots occur for interparticle distance of 1 to 1.5 nm among the individual Ag nanoparticles, as also validated by computational modeling, are identified for the highest signal enhancement of a molecular Raman reporter. Finally, the superior stability and batch-to-batch reproducibility of the developed SERS sensors are demonstrated and their potential with a proof-of-concept practical application in food-safety diagnostics for pesticide detection on fruit surfaces is explored.
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Registered trials
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