Evidence map›Paper›PMID 35670050›Full record

ArticleJournal of surgical oncology2022

Synovial sarcomas: A single surgeon experience of 130 cases.

Lorenzo Andreani, Edoardo Ipponi, Olimpia Mani, Ginevra Bayon, Alfio Damiano Ruinato, Fabio Cosseddu, Antonio D'Arienzo, Rodolfo Capanna

Open access · hybridAbstract read
In one paragraph

Article in Journal of surgical oncology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.6field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Lorenzo AndreaniDepartment of Orthopaedics and Trauma Surgery, University of Pisa, Pisa, Italy.ORCID http://orcid.org/0000-0002-8268-6987
Edoardo IpponiDepartment of Orthopaedics and Trauma Surgery, University of Pisa, Pisa, Italy.ORCID http://orcid.org/0000-0003-2107-6357
Olimpia ManiDepartment of Orthopaedics and Trauma Surgery, University of Pisa, Pisa, Italy.ORCID http://orcid.org/0000-0003-0276-6096
Ginevra BayonDepartment of Orthopaedics and Trauma Surgery, University of Pisa, Pisa, Italy.
Alfio Damiano RuinatoDepartment of Orthopaedics and Trauma Surgery, University of Pisa, Pisa, Italy.ORCID http://orcid.org/0000-0001-7092-7926
Fabio CossedduDepartment of Orthopaedics and Trauma Surgery, University of Pisa, Pisa, Italy.ORCID http://orcid.org/0000-0003-3416-7071
Antonio D'ArienzoDepartment of Orthopaedics and Trauma Surgery, University of Pisa, Pisa, Italy.ORCID http://orcid.org/0000-0003-1016-5944
Rodolfo CapannaDepartment of Orthopaedics and Trauma Surgery, University of Pisa, Pisa, Italy.ORCID http://orcid.org/0000-0001-7904-1267
University of Pisa · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSynovial sarcoma is a rare malignant tumor that generally requires a multidisciplinary therapeutic approach. In this study we report the experience of a single surgeon, evaluating surgical and oncological outcomes of the cases he treated through his 30 years carrier.

methodsWe enrolled patients treated surgically between 1988 and 2018. Surgical and medical treatments, as well as surgical and oncological results, were investigated.

resultsOne hundred and thirty cases were included. Surgical resection was carried out achieving wide margins in 90% of the cases. At their latest follow-up, 76 patients were continuously disease free, 16 were no evidence of disease, and other 16 were alive with disease. Twenty cases were dead of disease and two dead of other causes. Twenty-five patients (19%) had local recurrence of synovial sarcoma through their postoperative intercourse. Thirty-seven patients (28%) were diagnosed with at least a metastasis during their follow-up. The global survival of our population, at each patient's latest follow-up, was 82%. Cases with tumor size above 5 cm had a significantly higher risk to develop metastasis (p = 0.002).

conclusionsSynovial sarcoma is a threatening disease and represents a challenge for oncological physicians and surgeons. Early diagnosis and multidisciplinary approach are mandatory to limit the spread of synovial sarcomas, maximizing the effectiveness of surgery and the other treatments.

Indexed as

Sarcoma, SynovialSurgeonsDisease-Free SurvivalHumansMaleMargins of ExcisionNeoplasm Recurrence, LocalRetrospective Studiesoncological surgerysurvivalsynovial sarcomatumor resection

Identifiers

PMID35670050
PMCPMC9544735
OpenAlexW4281726047

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.