Evidence map›Paper›PMID 35669918›Full record

ArticleFrontiers in medicine2022

Inhaled CO

Elena Spinelli, Antonio Pesenti, Gianluca Lopez, Anna Damia, Francesco Damarco, Erica Garbelli, Gaia Dal Santo, Alessio Caccioppola, Giorgio Giudici, Virginia Figgiaconi and 8 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.9field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 3 institutions in 1 country.

Elena SpinelliDepartment of Anesthesia, Critical Care and Emergency, Fondazione Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.
Antonio PesentiDepartment of Anesthesia, Critical Care and Emergency, Fondazione Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.
Gianluca LopezDepartment of Biomedical Surgical and Dental Sciences, University of Milan, Milan, Italy.
Anna DamiaDepartment of Pathophysiology and Transplantation, University of Milan, Milan, Italy.
Francesco DamarcoDivision of Thoracic Surgery and Lung Transplantation, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.
Erica GarbelliDepartment of Pathophysiology and Transplantation, University of Milan, Milan, Italy.
Gaia Dal SantoDepartment of Pathophysiology and Transplantation, University of Milan, Milan, Italy.
Alessio CaccioppolaDepartment of Anesthesia, Critical Care and Emergency, Fondazione Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.
Giorgio GiudiciDepartment of Pathophysiology and Transplantation, University of Milan, Milan, Italy.
Virginia FiggiaconiDepartment of Pathophysiology and Transplantation, University of Milan, Milan, Italy.
Osvaldo BiancolilliDepartment of Anesthesia, Critical Care and Emergency, Fondazione Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.
Michele BattistinCenter for Preclinical Research, Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico, Milan, Italy.
Caterina LonatiCenter for Preclinical Research, Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico, Milan, Italy.
Valentina VairaDepartment of Pathophysiology and Transplantation, University of Milan, Milan, Italy.
Lorenzo RossoDepartment of Pathophysiology and Transplantation, University of Milan, Milan, Italy.
Stefano FerreroDepartment of Biomedical Surgical and Dental Sciences, University of Milan, Milan, Italy.
Stefano GattiCenter for Preclinical Research, Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico, Milan, Italy.
Tommaso MauriDepartment of Anesthesia, Critical Care and Emergency, Fondazione Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.
Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico · ITUniversity of Milan · ITOspedale Maggiore · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Unilateral ligation of the pulmonary artery (UPAL) induces bilateral lung injury in pigs undergoing controlled mechanical ventilation. Possible mechanisms include redistribution of ventilation toward the non-ligated lung and hypoperfusion of the ligated lung. The addition of 5% CO Methods: Healthy pigs underwent left UPAL and were allocated for 48 h to the following: Volume-controlled ventilation (VCV) with V Results: In the left ligated lung, injury was prevented only in the FiCO Conclusion: In a model of UPAL, inhaled CO

Indexed as

inhaled CO2mechanical ventilationpulmonary perfusiontherapeutic hypercapniaventilator-induced lung injury

Identifiers

PMID35669918
PMCPMC9163369
OpenAlexW4280568311

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.