Evidence map›Paper›PMID 35669898›Full record

ArticleInternational cancer conference journal2022

Pathologic complete response with pembrolizumab plus axitinib in metastatic renal cell carcinoma.

Kazuki Shimizu, Satoshi Tamada, Yudai Matsuoka, Ishun Go, Satoshi Okumura, Masao Ogawa, Tetsuji Ohmachi

Open access · greenAbstract readCase Reports
In one paragraph

Article in International cancer conference journal, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
4.4field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. Trial
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Kazuki ShimizuDepartment of Urology, Bell Land General Hospital, 500-3, Higashiyama, Naka-ku, Sakai City, Osaka 599-8247 Japan.
Satoshi TamadaDepartment of Urology, Bell Land General Hospital, 500-3, Higashiyama, Naka-ku, Sakai City, Osaka 599-8247 Japan.ORCID 0000-0002-7102-3408
Yudai MatsuokaDepartment of Urology, Bell Land General Hospital, 500-3, Higashiyama, Naka-ku, Sakai City, Osaka 599-8247 Japan.
Ishun GoDepartment of Urology, Bell Land General Hospital, 500-3, Higashiyama, Naka-ku, Sakai City, Osaka 599-8247 Japan.
Satoshi OkumuraDepartment of Surgery, Bell Land General Hospital, Sakai City, Japan.
Masao OgawaDepartment of Surgery, Bell Land General Hospital, Sakai City, Japan.
Tetsuji OhmachiDepartment of Urology, Bell Land General Hospital, 500-3, Higashiyama, Naka-ku, Sakai City, Osaka 599-8247 Japan.
Berurando General Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Immunotherapy-based combinations have played a central role in the treatment of metastatic renal cell carcinoma, and long-term survival of patients is expected. In this context, it is clear that a certain number of patients can achieve a complete response. However, the diagnosis of complete response is usually based on imaging, and there are few cases of pathological complete response. In this study, we report a case of a patient with metastatic renal cell carcinoma who was treated with pembrolizumab plus axitinib, followed by resection of the primary tumor and metastatic lesions, and pathologically achieved a complete response.

Indexed as

Complete responseMetastatic renal cell carcinomaPathologicalPembrolizumab plus axitinib

Identifiers

PMID35669898
PMCPMC9163222
OpenAlexW4224300382

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.