Evidence map›Paper›PMID 35669786›Full record

ReviewFrontiers in immunology2022

Novel Immune Checkpoints in Esophageal Cancer: From Biomarkers to Therapeutic Targets.

Xueyin Zhou, Ting Ren, Hongyuan Zan, Chunyan Hua, Xufeng Guo

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in immunology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
3.3field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 32 citations in OpenAlex.

  1. Review
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  11. EZH2 elicits CD8Communications biology · 2024
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  13. NApoptosis : an international journal on programmed cell death · 2024
    Article
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  18. From bench to bedside: targeting lymphocyte activation gene 3 as a therapeutic strategy for autoimmune diseases.Inflammation research : official journal of the European Histamine Research Society ... [et al.] · 2023
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Xueyin ZhouSchool of Medicine, Wenzhou Medical University, Wenzhou, China.
Ting RenDepartment of Thoracic Surgery, Shanghai Chest Hospital, Shanghai Jiao Tong University, Shanghai, China.
Hongyuan ZanSchool of Medicine, Wenzhou Medical University, Wenzhou, China.
Chunyan HuaSchool of Basic Medical Sciences, Wenzhou Medical University, Wenzhou, China.
Xufeng GuoDepartment of Thoracic Surgery, Shanghai Chest Hospital, Shanghai Jiao Tong University, Shanghai, China.
Wenzhou Medical University · CNShanghai Jiao Tong University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Esophageal cancer ranks as the sixth most common cause of cancer death worldwide. Due to the limited efficacy of conventional therapeutic strategies, including surgery, chemotherapy, and radiotherapy, treatments are still far from satisfactory in terms of survival, prompting the search for novel treatment methods. Immune checkpoints play crucial roles in immune evasion mediated by tumor cells, and successful clinical outcomes have been achieved

Indexed as

Esophageal NeoplasmsProgrammed Cell Death 1 ReceptorBiomarkersHumansImmune Checkpoint InhibitorsImmunotherapyBiomarkersImmune Checkpoint InhibitorsProgrammed Cell Death 1 Receptorbiomarkeresophageal cancerimmunotherapyLAG-3TIGITTIM-3

Identifiers

PMID35669786
PMCPMC9163322
OpenAlexW4280638672

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.