Evidence map›Paper›PMID 35669781›Full record

ArticleFrontiers in immunology2022

Malondialdehyde Acetaldehyde-Adduction Changes Surfactant Protein D Structure and Function.

Claire G Nissen, Deanna D Mosley, Kusum K Kharbanda, Dawn M Katafiasz, Kristina L Bailey, Todd A Wyatt

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 7 citations in OpenAlex.

  1. Alcohol's Effects on the Lung and Lung Disease.Alcohol research : current reviews · 2025
    Pooled it
  2. Review
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Claire G NissenDepartment of Environmental, Agricultural and Occupational Health, College of Public Health, University of Nebraska Medical Center, Omaha, NE, United States.
Deanna D MosleyDepartment of Internal Medicine, College of Medicine, University of Nebraska Medical Center, Omaha, NE, United States.
Kusum K KharbandaDepartment of Internal Medicine, College of Medicine, University of Nebraska Medical Center, Omaha, NE, United States.
Dawn M KatafiaszDepartment of Internal Medicine, College of Medicine, University of Nebraska Medical Center, Omaha, NE, United States.
Kristina L BaileyDepartment of Internal Medicine, College of Medicine, University of Nebraska Medical Center, Omaha, NE, United States.
Todd A WyattDepartment of Environmental, Agricultural and Occupational Health, College of Public Health, University of Nebraska Medical Center, Omaha, NE, United States.
University of Nebraska Medical Center · USVA Nebraska Western Iowa Health Care System · US

Funding

Impaired phospholipid methylation results in decreased lipid droplet lipolysis: Role in hepatic steatosisR01AA026723 · NIAAA · UNIVERSITY OF NEBRASKA MEDICAL CENTER · PI KHARBANDA, KUSUM K. · 2018 to 2022
$1.6M
Mucociliary clearance in agingR01AG053553 · NIA · UNIVERSITY OF NEBRASKA MEDICAL CENTER · PI BAILEY, KRISTINA L · 2016 to 2020
$1.5M
Lung Innate COVID-19 Defense Specific to Veterans Risk CharacteristicsI01BX005413 · VA · OMAHA VA MEDICAL CENTER · PI BAILEY, KRISTINA L, WYATT, TODD A · 2021 to 2022
–
BLRD VA I01 BX003635BLRD VA I01 BX004053BLRD VA I01 BX005413BLRD VA IK6 BX005962NIAAA NIH HHS R01 AA026723NIA NIH HHS R01 AG053553
6 · The paper itself

Abstract

Alcohol consumption with concurrent cigarette smoking produces malondialdehyde acetaldehyde (MAA)-adducted lung proteins. Lung surfactant protein D (SPD) supports innate immunity

Indexed as

AcetaldehydeAlcoholismHumansLungMalondialdehydePulmonary Surfactant-Associated Protein DAcetaldehydeMalondialdehydePulmonary Surfactant-Associated Protein Dadductionalcoholaldehydeslungpneumoniasurfactant

Identifiers

PMID35669781
PMCPMC9164268
OpenAlexW4280547966

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.