Evidence map›Paper›PMID 35669730›Full record

ArticleBioMed research international2022

Mitochondrial-Targeted Antioxidant Peptide SS31 Prevents RPE Cell Death under Oxidative Stress.

Yuan He, Zejun Chen, Ruixue Zhang, Zhuoya Quan, Yun Xu, Beilei He, Yuan Ren

RetractedAbstract readRetracted Publication
In one paragraph

Article in BioMed research international, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It has been retracted, and should not be counted. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Common methods in mitochondrial research (Review).International journal of molecular medicine · 2022
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors.

Yuan HeDepartment of Ophthalmology, The Second Affiliated Hospital of Xi'an Medical University, Xi'an, China.ORCID https://orcid.org/0000-0001-7692-5577
Zejun ChenXi'an Medical University, Xi'an, China.
Ruixue ZhangDepartment of Ophthalmology, The Second Affiliated Hospital of Xi'an Medical University, Xi'an, China.ORCID https://orcid.org/0000-0002-4988-4922
Zhuoya QuanDepartment of Ophthalmology, The Second Affiliated Hospital of Xi'an Medical University, Xi'an, China.ORCID https://orcid.org/0000-0002-5933-8087
Yun XuXi'an Medical University, Xi'an, China.
Beilei HeXi'an Medical University, Xi'an, China.
Yuan RenDepartment of Ophthalmology, The Second Affiliated Hospital of Xi'an Medical University, Xi'an, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This work aims at investigating the protective effects of the mitochondria-targeted peptide SS31, on mitochondria function, preventing human retinal pigment epithelial cell-19 (ARPE-19) cell apoptosis. The ARPE-19 cells were subjected to 24 h of intervention with H

Indexed as

AntioxidantsHydrogen PeroxideApoptosisbcl-2-Associated X ProteinCaspase 3Cell SurvivalHumansMitochondriaOxidative StressProto-Oncogene Proteins c-bcl-2Reactive Oxygen SpeciesAntioxidantsbcl-2-Associated X ProteinCaspase 3Hydrogen PeroxideProto-Oncogene Proteins c-bcl-2Reactive Oxygen Species

Identifiers

PMID35669730
PMCPMC9167025

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.