Evidence map›Paper›PMID 35669533›Full record

ArticleAnalysis & sensing2021

Jaspal Singh, Eul Hyun Suh, Gaurav Sharma, Jun Chen, Edward P Hackett, Xiaodong Wen, A Dean Sherry, Chalermchai Khemtong, Craig R Malloy, Jae Mo Park and 1 more

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Analysis & sensing, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.5field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 6 citations in OpenAlex.

  1. Deuterated pH Probes Based on Ketoglutarate for Magnetic Resonance.Journal of the American Chemical Society · 2026
    Article
  2. Article
  3. Article
  4. StereoPHIP: Stereoselective Parahydrogen-Induced Polarization.Angewandte Chemie (International ed. in English) · 2023
    Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Jaspal SinghAdvanced Imaging Research Center, University of Texas South-western Medical Center, Dallas, TX.
Eul Hyun SuhAdvanced Imaging Research Center, University of Texas South-western Medical Center, Dallas, TX.
Gaurav SharmaAdvanced Imaging Research Center, University of Texas South-western Medical Center, Dallas, TX.
Jun ChenAdvanced Imaging Research Center, University of Texas South-western Medical Center, Dallas, TX.
Edward P HackettAdvanced Imaging Research Center, University of Texas South-western Medical Center, Dallas, TX.
Xiaodong WenAdvanced Imaging Research Center, University of Texas South-western Medical Center, Dallas, TX.
A Dean SherryAdvanced Imaging Research Center, University of Texas South-western Medical Center, Dallas, TX.
Chalermchai KhemtongDepartment of Medicine, Division of Endocrinology, Diabetes and Metabolism, University of Florida, Gainesville, FL and Department of Biochemistry and Molecular Biology, University of Florida, Gainesville, FL.
Craig R MalloyAdvanced Imaging Research Center, University of Texas South-western Medical Center, Dallas, TX.
Jae Mo ParkAdvanced Imaging Research Center, University of Texas South-western Medical Center, Dallas, TX.
Zoltan KovacsAdvanced Imaging Research Center, University of Texas South-western Medical Center, Dallas, TX.
Southwestern Medical Center · USUniversity of Florida Health · US

Funding

TR&D 3: Imaging Carbohydrate MetabolismP41EB015908 · NIBIB · UT SOUTHWESTERN MEDICAL CENTER · PI MALLOY, CRAIG R · 2012 to 2021
$10.9M
Esterase-sensitive hyperpolarized 13C probes for simultaneous imaging of pH and energy metabolismR01EB027698 · NIBIB · UT SOUTHWESTERN MEDICAL CENTER · PI KHEMTONG, CHALERMCHAI · 2020 to 2023
$1.3M
NIBIB NIH HHS P41 EB015908NIBIB NIH HHS R01 EB027698
6 · The paper itself

Abstract

The TCA cycle is a central metabolic pathway for energy production and biosynthesis. A major control point of metabolic flux through the cycle is the decarboxylation of 2-ketoglutarate by the TCA cycle enzyme 2-ketoglutarate dehydrogenase (2-KGDH). In this project, we developed

Indexed as

hyperpolarizationisotopic labelingketoglutaratesNMR spectroscopyTCA cycle

Identifiers

PMID35669533
PMCPMC9165698
OpenAlexW3188828938

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.