Evidence map›Paper›PMID 35669526›Full record

ArticleResuscitation plus2022

Mechanical life support algorithm developed by simulation for inpatient emergency management of recipients of implantable left ventricular assist devices.

Waqas Akhtar, Brigitte Gamble, Kristine Kiff, Agnieszka Wypych-Zych, Binu Raj, Junko Takata, Fernando Riesgo Gil, Ana Hurtado, Alex Rosenberg, Christopher T Bowles

Abstract read
In one paragraph

Article in Resuscitation plus, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Guideline
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Waqas AkhtarHarefield Hospital, Hill End Road, Harefield, Uxbridge UB96JH, United Kingdom.
Brigitte GambleHarefield Hospital, Hill End Road, Harefield, Uxbridge UB96JH, United Kingdom.
Kristine KiffHarefield Hospital, Hill End Road, Harefield, Uxbridge UB96JH, United Kingdom.
Agnieszka Wypych-ZychHarefield Hospital, Hill End Road, Harefield, Uxbridge UB96JH, United Kingdom.
Binu RajHarefield Hospital, Hill End Road, Harefield, Uxbridge UB96JH, United Kingdom.
Junko TakataHarefield Hospital, Hill End Road, Harefield, Uxbridge UB96JH, United Kingdom.
Fernando Riesgo GilHarefield Hospital, Hill End Road, Harefield, Uxbridge UB96JH, United Kingdom.
Ana HurtadoHarefield Hospital, Hill End Road, Harefield, Uxbridge UB96JH, United Kingdom.
Alex RosenbergHarefield Hospital, Hill End Road, Harefield, Uxbridge UB96JH, United Kingdom.
Christopher T BowlesHarefield Hospital, Hill End Road, Harefield, Uxbridge UB96JH, United Kingdom.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Published guidance concerning emergency management of left ventricular assist device (LVAD) recipients is both limited and lacking in consensus which increases the risk of delayed and/or inappropriate actions. Methods: In our specialist tertiary referral centre we developed, by iteration, a novel in-hospital resuscitation algorithm for LVAD emergencies which we validated through simulation and assessment of our multi-disciplinary team. A Mechanical Life Support course was established to provide theoretical and practical education combined with simulation to consolidate knowledge and confidence in algorithm use. We assessed these measures using confidence scoring, a key performance indicator (the time taken to restart LVAD function) and a multiple-choice question (MCQ) examination. Results: The mean baseline staff confidence score in management of LVAD emergencies was 2.4 ± 1.2 out of a maximum of 5 (n = 29). After training with simulation, mean confidence score increased to 3.5 ± 0.8 (n = 13).Clinical personnel who were provided with the novel resuscitation algorithm were able to reduce time taken to restart LVAD function from a mean value of 49 ± 8.2 seconds (pre-training) to 20.4 ± 5 seconds (post-training) (n = 42, p < 0.0001).The Mechanical Life Support course increased mean confidence from 2.5 ± 1.2 to 4 ± 0.6 (n = 44, p < 0.0001) and mean MCQ score from 18.7 ± 3.4 to 22.8 ± 2.6, out of a maximum of 28 (n = 44, p < 0.0001). Conclusion: We present a simplified LVAD Advanced Life Support algorithm to aid the crucial first minutes of resuscitation where basic interventions are likely to be critical in assuring good patient outcomes.

Indexed as

Advanced life supportALS, Advanced Life SupportCALS, Cardiac Advanced Life SupportCardiac arrestCPR, Cardio-Pulmonary ResuscitationDNAR, do not attempt resuscitation orderECMO, Extracorporeal Membrane OxygenationETCO2, End Tidal Carbon Dioxide, kPa KilopascalLeft ventricular assist deviceLVADLVAD, Left Ventricular Assist DeviceMAP, Mean Arterial PressureMCQ, multiple-choice examMDT, multi-disciplinary teamMechanical circulatory supportMLS, Mechanical Life SupportResuscitationVF, Ventricular FibrillationVT, Ventricular Tachycardia

Identifiers

PMID35669526
PMCPMC9162943

What OpenQuestion holds

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LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.