ArticleInternational journal of nephrology2022
Comparison of Laboratory Diagnosis of Urinary Tract Infections Based on Leukocyte and Bacterial Parameters Using Standardized Microscopic and Flow Cytometry Methods.
Article in International journal of nephrology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed, 8 citations in OpenAlex.
- Diagnostic Accuracy of Urine Flow Cytometry (UF) in Urinary Tract Infection (UTI) Detection and Management: A Systematic Review and Meta-Analysis.Diagnostics (Basel, Switzerland) · 2026Review
- Article
- Prevalence and risk factors of asymptomatic bacteriuria in community-dwelling Korean adults.PloS one · 2026Article
- Clinical Usefulness of Early Evaluation of the Bacteriological Effect of Antibiotics Administered as Empiric Therapy Using the Fully Automated Urine Particle Analyzer UF-5000 in Febrile Urinary Tract Infections.International journal of urology : official journal of the Japanese Urological Association · 2025Article
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Authors and funding
9 authors at 3 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Rapid and reliable tests are essential for the diagnostic laboratory confirmation of urinary tract infections (UTIs). Until now, UTI has been confirmed by the microbiology culture of urine, requiring at least 48-hour turnaround time (TAT), with a standardized microscopic method being widely favored. Automated urine flow cytometry, however, has recently been used to improve the rapid TAT by analyzing the urine sediment. This study therefore aimed to compare the diagnostic value of the Shih-Yung conventional microscopic and urine flow cytometry methods in the detection of leukocyte and bacterial parameters of patients with UTIs in an outpatient clinic. Methods: A cross-sectional study was conducted on a total of 100 patients. Seventy urine samples were positive for leukocytes and nitrite chemistry, and 30 were negative for both. The measurements of urine leukocytes and bacteria were compared between Sysmex UF-5000 urine flow cytometry and the Shih-Yung method. The diagnostic value was obtained from ROC analysis of urine flow cytometry and the culture. Results: A leukocyte cutoff value of 87.2/ Conclusions: The Shih-Yung method showed consistent agreement with urine flow cytometry for the detection of leukocytes and bacteria. The use of certain cutoffs for bacterial and leukocyte parameters in urine flow cytometry demonstrated very good performance in detecting acquired symptomatic UTIs.
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Registered trials
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