Evidence map›Paper›PMID 35669403›Full record

ArticleFrontiers in pediatrics2022

Clinical and Neurodevelopmental Characteristics of

Silvia Bucci, Luana Coltella, Ludovica Martini, Alessandra Santisi, Domenico Umberto De Rose, Livia Piccioni, Francesca Campi, Maria Paola Ronchetti, Daniela Longo, Giulia Lucignani and 2 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in pediatrics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
3.6field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 23 citations in OpenAlex.

  1. Article
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  4. Cranial ultrasound in neonatal brain infections.Developmental medicine and child neurology · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Silvia BucciDepartment of Neurosciences, "Bambino Gesù" Children's Hospital Scientific Hospitalization and Treatment Institute (IRCCS), Rome, Italy.
Luana ColtellaDepartment of Microbiology and Virology, "Bambino Gesù" Children's Hospital Scientific Hospitalization and Treatment Institute (IRCCS), Rome, Italy.
Ludovica MartiniMedical and Surgical Department of Fetus-Newborn-Infant, "Bambino Gesù" Children's Hospital Scientific Hospitalization and Treatment Institute (IRCCS), Rome, Italy.
Alessandra SantisiMedical and Surgical Department of Fetus-Newborn-Infant, "Bambino Gesù" Children's Hospital Scientific Hospitalization and Treatment Institute (IRCCS), Rome, Italy.
Domenico Umberto De RoseMedical and Surgical Department of Fetus-Newborn-Infant, "Bambino Gesù" Children's Hospital Scientific Hospitalization and Treatment Institute (IRCCS), Rome, Italy.
Livia PiccioniDepartment of Microbiology and Virology, "Bambino Gesù" Children's Hospital Scientific Hospitalization and Treatment Institute (IRCCS), Rome, Italy.
Francesca CampiMedical and Surgical Department of Fetus-Newborn-Infant, "Bambino Gesù" Children's Hospital Scientific Hospitalization and Treatment Institute (IRCCS), Rome, Italy.
Maria Paola RonchettiMedical and Surgical Department of Fetus-Newborn-Infant, "Bambino Gesù" Children's Hospital Scientific Hospitalization and Treatment Institute (IRCCS), Rome, Italy.
Daniela LongoDepartment of Imaging, "Bambino Gesù" Children's Hospital Scientific Hospitalization and Treatment Institute (IRCCS), Rome, Italy.
Giulia LucignaniDepartment of Imaging, "Bambino Gesù" Children's Hospital Scientific Hospitalization and Treatment Institute (IRCCS), Rome, Italy.
Andrea DottaMedical and Surgical Department of Fetus-Newborn-Infant, "Bambino Gesù" Children's Hospital Scientific Hospitalization and Treatment Institute (IRCCS), Rome, Italy.
Cinzia AuritiMedical and Surgical Department of Fetus-Newborn-Infant, "Bambino Gesù" Children's Hospital Scientific Hospitalization and Treatment Institute (IRCCS), Rome, Italy.
Bambino Gesù Children's Hospital · ITIstituti di Ricovero e Cura a Carattere Scientifico · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Non-polio-enteroviruses (EV) and human parechoviruses (HPeV) are small RNA viruses, which in newborns cause infections with a wide range of severity. Today molecular biology tools allow us to diagnose viral meningitis in neonates, sparing patients from useless antibiotics. Data on neurodevelopmental outcome of children who contract enterovirus meningitis in early childhood are still limited in the literature. Aims: To evaluate the neurodevelopmental outcome of newborns with documented e Methods: Results: We observed longitudinally 30 children, born at term (mean GA 39.7 ± 0.8 weeks, mean birthweight was 3,457 ± 405 grams), who contracted Conclusions: Early enterovirus infections can be associated to brain MRI abnormalities, more frequently the earlier the infection. Although within a normal range, our children with pathological brain MRI scored significantly lower than those with normal brain MRI on cognitive subscale at 12 months of life.

Indexed as

infantsneurodevelopmentnewbornsoutcomesviral meningitisviruses

Identifiers

PMID35669403
PMCPMC9165715
OpenAlexW4280488287

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.