Evidence map›Paper›PMID 35669353›Full record

ArticleIndian journal of hematology & blood transfusion : an official journal of Indian Society of Hematology and Blood Transfusion2022

Single Dose of Ivermectin is not Useful in Patients with Hematological Disorders and COVID-19 Illness: A Phase II B Open Labelled Randomized Controlled Trial.

Biju George, Mahesh Moorthy, Uday Kulkarni, Sushil Selvarajan, Priscilla Rupali, D J Christopher, T Balamugesh, Winsley Rose, Kavitha M Lakshmi, Anup J Devasia and 5 more

Open access · bronzeAbstract read
In one paragraph

Article in Indian journal of hematology & blood transfusion : an official journal of Indian Society of Hematology and Blood Transfusion, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 2 pooled it
0.5field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 2 syntheses or guidelines pooled it, 5 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. Perspective: repurposed drugs for COVID-19.Archives of medical science : AMS · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 1 institution in 1 country.

Biju George *Department of Haematology, Christian Medical College, Vellore, India.ORCID 0000-0002-9847-9501
Mahesh Moorthy *Department of Clinical Virology, Christian Medical College, Vellore, India.
Uday KulkarniDepartment of Haematology, Christian Medical College, Vellore, India.
Sushil SelvarajanDepartment of Haematology, Christian Medical College, Vellore, India.
Priscilla RupaliDepartment of Infectious Diseases, Christian Medical College, Vellore, India.
D J ChristopherDepartment of Pulmonary Medicine, Christian Medical College, Vellore, India.
T BalamugeshDepartment of Pulmonary Medicine, Christian Medical College, Vellore, India.
Winsley RoseDepartment of Paediatric Infectious Diseases, Christian Medical College, Vellore, India.
Kavitha M LakshmiDepartment of Haematology, Christian Medical College, Vellore, India.
Anup J DevasiaDepartment of Haematology, Christian Medical College, Vellore, India.
N A FouziaDepartment of Haematology, Christian Medical College, Vellore, India.
Anu KorulaDepartment of Haematology, Christian Medical College, Vellore, India.
Sharon LionelDepartment of Haematology, Christian Medical College, Vellore, India.
Aby AbrahamDepartment of Haematology, Christian Medical College, Vellore, India.
Vikram MathewsDepartment of Haematology, Christian Medical College, Vellore, India.
Christian Medical College, Vellore · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Repurposed drugs may reduce morbidity and mortality in patients with hematological disorders who develop COVID-19 illness. 112 patients with predominantly hematological illnesses were randomized to receive standard of care, ivermectin 12 mg [Iv 12] or 24 mg [Iv24] for asymptomatic, mild, or moderate COVID 19 illness. Serial respiratory samples for rRT-PCR samples were sent on Day 3, 5 and 7. rRT-PCR negativity and ≥ 2 log

Indexed as

COVID-19IvermectinSurvivalSymptom progression

Identifiers

PMID35669353
PMCPMC9135993
OpenAlexW4282048309

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.