Evidence map›Paper›PMID 35669297›Full record

ArticleClinical diabetes : a publication of the American Diabetes Association2022

Medication Optimization for New Initiators of Empagliflozin for Diabetic Kidney Disease.

Andrew A Swanner, Chelsea E Hawley, Kay Li, Laura K Triantafylidis, Jiahua Li, Julie M Paik

Open access · bronzeAbstract read
In one paragraph

Article in Clinical diabetes : a publication of the American Diabetes Association, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Andrew A SwannerPharmacy Department, VA Boston Healthcare System, Boston.
Chelsea E HawleyNew England Geriatric Research, Education and Clinical Center, VA Boston Healthcare System, Boston.
Kay LiPharmacy Department, VA Boston Healthcare System, Boston.
Laura K TriantafylidisPharmacy Department, VA Boston Healthcare System, Boston.ORCID https://orcid.org/0000-0002-8818-9535
Jiahua LiRenal Section, VA Boston Healthcare System, Boston.
Julie M PaikNew England Geriatric Research, Education and Clinical Center, VA Boston Healthcare System, Boston.ORCID https://orcid.org/0000-0002-1315-5445
VA Boston Healthcare System · USBrigham and Women's Hospital · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Sodium-glucose cotransporter 2 (SGLT2) inhibitors are recommended agents for the treatment of diabetic kidney disease (DKD). Additionally, SGLT2 inhibitors lower blood glucose, decrease blood pressure, and can be useful for volume management. For these reasons, we hypothesized that initiating SGLT2 inhibitor therapy may be associated with deprescribing of other medications in patients with DKD. We compared medication lists at SGLT2 inhibitor initiation and 6 months post-initiation in 21 patients with DKD who were followed in our interprofessional outpatient nephrology clinic to evaluate deprescribing patterns in diabetes, hypertension, and diuretic medications. Six months of SGLT2 inhibitor therapy in patients with DKD was associated with deprescribing of high-risk diabetes agents, antihypertensives, and loop diuretics with minimal changes in A1C and fewer adverse events.

Identifiers

PMID35669297
PMCPMC9160537
OpenAlexW3210519870

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.