Evidence map›Paper›PMID 35669019›Full record

ArticleIndian journal of orthopaedics2022

Disc Degeneration in Lumbar Spine of Asymptomatic Young Adults: A Descriptive Cross-Sectional Study.

Manish Chadha, Amit Srivastava, Vipin Kumar, Anupama Tandon

Open access · greenAbstract read
In one paragraph

Article in Indian journal of orthopaedics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.2field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 9 citations in OpenAlex.

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  2. PDGF-Releasing Hydrogels for Enhanced Proliferation of Human Nucleus Pulposus Cells.Journal of biomedical materials research. Part A · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Manish ChadhaDepartment of Orthopaedics, University College of Medical Sciences and Guru Teg Bahadur Hospital, Dilshad Garden, Delhi, 110095 India.
Amit SrivastavaDepartment of Orthopaedics, University College of Medical Sciences and Guru Teg Bahadur Hospital, Dilshad Garden, Delhi, 110095 India.
Vipin KumarDepartment of Orthopaedics, University College of Medical Sciences and Guru Teg Bahadur Hospital, Dilshad Garden, Delhi, 110095 India.
Anupama TandonDepartment of Radio-Diagnosis, University College of Medical Sciences and Guru Teg Bahadur Hospital, Delhi, 110095 India.
Guru Teg Bahadur Hospital · INUniversity College of Medical Sciences · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: This descriptive cross-sectional observational study aimed to investigate the prevalence of various types of disc degeneration in the lumbar spine of asymptomatic young adults. The disc degeneration of lumbar spine could be due to age-related physiological changes than to pathological changes in asymptomatic people. Due to the ethnic and racial differences in lifestyle, it is proposed that the prevalence of disc degeneration in the normal population in different region of the world would differ. There are scarce data on the Indian population on the same. Methods: Fifty individuals between 15 and 30 years of age, with no history of low back pain undergoing MR imaging for spinal pathology other than the lumbar spine, were included in the study. Various abnormalities (herniation HN, annular fissure AF, nuclear degeneration ND) were recorded and their prevalence was calculated by disc counts (DC) and person count (PC). DC is the number of discs with degeneration and PC is the number of patients with disc degeneration. Results: 56% asymptomatic individuals were found to have either HN or AF or ND at one or more levels. The DC of disc degeneration was 20.8% and it was most commonly observed in L4-L5 intervertebral disc (38%) followed by L5-S1 disc (30%). Thirteen individuals had disc degeneration at single level, 12 at two levels and 3 individuals at all the five lumbar intervertebral disc levels. Conclusion: The current study showed a high prevalence of disc degeneration (either HN, AF or ND) in young asymptomatic individuals. Even if the MRI shows disc degeneration, patients can be asymptomatic and one needs to correlate the symptoms with the MRI. The limitations of the current study are small numbers of patients from a localized geographical area; hence, we recommend a larger multi-centric study as a follow-up.

Indexed as

AsymptomaticIntervertebral disc degenerationMagnetic resonance imagingSpineYoung adults

Identifiers

PMID35669019
PMCPMC9123103
OpenAlexW4220994748

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.