Evidence map›Paper›PMID 35668858›Full record

ArticleInfection and drug resistance2022

Circulation of Dengue Virus Serotype 2 in Humans and Mosquitoes During an Outbreak in El Quseir City, Egypt.

Asmaa M El-Kady, Heba A Osman, Mohamed Farouk Alemam, Dina Marghani, Mohammed A Shanawaz, Majed H Wakid, Wafa Abdullah I Al-Megrin, Hatem A Elshabrawy, Osama H Abdella, Khaled S Allemailem and 2 more

Erratum issuedOpen access · goldAbstract read
In one paragraph

Article in Infection and drug resistance, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
1.4field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 7 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Increase in dengue fever in travellers returning from Egypt, Germany 2023.Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin · 2024
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

12 authors at 7 institutions in 3 countries.

Asmaa M El-KadyDepartment of Medical Parasitology, Faculty of Medicine, South Valley University, Qena, Egypt.ORCID 0000-0002-9294-2630
Heba A OsmanDepartment of Gastroenterology and Tropical Medicine, Faculty of Medicine, South Valley University, Qena, Egypt.ORCID 0000-0001-6302-3443
Mohamed Farouk AlemamDepartment of Clinical Pathology, Faculty of Medicine, South Valley University, Qena, Egypt.
Dina MarghaniClinical Laboratory Science Department, Faculty of Applied Medical Science, Taibah University, Medina, Kingdom of Saudi Arabia.
Mohammed A ShanawazDepartment of Public Health, Applied Medical Sciences College, Albaha University, Albaha, Saudi Arabia.ORCID 0000-0001-5253-5910
Majed H WakidDepartment of Medical Laboratory Technology, Faculty of Applied Medical Sciences, King Abdulaziz University, Jeddah 21589, Saudi Arabia, Jeddah, 21589, Saudi Arabia.ORCID 0000-0003-4941-5373
Wafa Abdullah I Al-MegrinDepartment of Biology, College of Science, Princess Nourah bint Abdulrahman University, Riyadh, 11671, Saudi Arabia.
Hatem A ElshabrawyDepartment of Molecular and Cellular Biology, College of Osteopathic Medicine, Sam Houston State University, Conroe, TX, 77304, USA.
Osama H AbdellaDepartment of Medical Parasitology, Faculty of Medicine, South Valley University, Qena, Egypt.ORCID 0000-0001-6605-3373
Khaled S AllemailemDepartment of Medical Laboratories, College of Applied Medical Sciences, Qassim University, Buraydah, 51452, Saudi Arabia.ORCID 0000-0002-6486-9835
Ahmad AlmatroudiDepartment of Medical Laboratories, College of Applied Medical Sciences, Qassim University, Buraydah, 51452, Saudi Arabia.ORCID 0000-0002-1491-6402
Mostafa I El-AmirDepartment of Medical Microbiology and Immunology, Faculty of Medicine, South Valley University, Qena, Egypt.ORCID 0000-0001-6682-0309
South Valley University · EGQassim University · SAAl Baha University · SAKing Abdulaziz University · SAPrincess Nourah bint Abdulrahman University · SASam Houston State University · USTaibah University · SA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: In recent decades, the rate of infection with dengue virus (DENV) has risen significantly, now affecting nearly 400 million individuals annually. Dengue fever among humans is caused via specific mosquito vectors bites. Sporadic cases have been reported in Egypt. The goal of this study was to identify the serotype of the DENV outbreak in both human and mosquito vector along the coast of the Red Sea, Upper Egypt, in 2017. Identification of the serotype of the virus may help identify its source and assist in applying epidemiological and control measures. Materials and Methods: The current study was carried out in El Quseir City, Red Sea Governorate, Upper Egypt, on 144 patients complaining of symptoms indicative of dengue fever at the time of the 2017 Egypt outbreak. Human blood samples and the mosquito reservoirs were identified as having dengue virus infection serologically and molecularly. Results: Overall, 97 (67.4%) patients were positive for dengue virus IgM antibodies. Molecular examination of the human samples and pools of mosquitoes revealed that DENV-2 virus was the serotype responsible for the outbreak. Only one pool of female mosquitoes containing Conclusion: This was the first serotyping of the DENV responsible for dengue virus outbreak in Egypt in 2017. Determining the serotype of dengue virus can help to avoid and monitor outbreaks. The serotype identified in this study was DENV-2, while DENV-1 was the serotype found in the previous outbreak in 2015 in the province of Assiut. This study thus raises concerns that a new dengue serotype could have been introduced into Egypt. It is necessary for a comprehensive risk assessment to be carried out in the country, including an entomological survey, to assess the presence and potential geographical expansion of mosquito vectors there.

Indexed as

dengue feverhumanmosquitomultiplex PCRserotypingUpper Egypt

Identifiers

PMID35668858
PMCPMC9165652
OpenAlexW4281897995

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.