Evidence map›Paper›PMID 35668701›Full record

ArticleTechnology in cancer research & treatment

Application of Controlled Hypotension During Surgery for Spinal Metastasis.

Rong-Xing Ma, Rui-Qi Qiao, Ming-You Xu, Rui-Feng Li, Yong-Cheng Hu

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Technology in cancer research & treatment. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07238101 (Hemodynamic Effects of Fentanyl and Dexmedetomidine in Spine Surgery), which is not on this map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07238101 phase4completednot on this map

Hemodynamic Effects of Fentanyl and Dexmedetomidine in Spine Surgery

TypeinterventionalSponsorUniversitas Sumatera UtaraRan2024 to 2025Enrolled50ConditionsSpine Surgery, Hemodynamic Stability During AnesthesiaArmsDexmedetomidine, fentanyl
3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 10 citations in OpenAlex.

  1. Comparison of intraoperative blood loss and perioperative complications between preoperative embolization and nonembolization combined with spinal tumor surgeries: a systematic review and meta-analysis.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2023
    Pooled it
  2. Trial
  3. Trial
  4. Article
  5. Article
  6. Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Rong-Xing Ma74768Tianjin Hospital, Tianjin, China.
Rui-Qi Qiao74768Tianjin Hospital, Tianjin, China.
Ming-You Xu74768Tianjin Hospital, Tianjin, China.
Rui-Feng Li74768Tianjin Hospital, Tianjin, China.
Yong-Cheng Hu74768Tianjin Hospital, Tianjin, China.ORCID 0000-0002-9846-6735
Tianjin Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

With advances in tumor treatment, metastasis to bone is increasing, and surgery has become the only choice for most terminal patients. However, spinal surgery has a high risk and is prone to heavy bleeding. Controlled hypotension during surgery has outstanding advantages in reducing intraoperative bleeding and ensuring a clear field of vision, thus avoiding damage to important nerves and vessels. Antihypertensive drugs should be carefully selected after considering the patient's age, different diseases, etc, and a single or combined regimen can be used. Hypotension also inevitably leads to a decrease in perfusion of important organs, so the threshold of hypotension and the maintenance time of hypotension should be strictly limited, and the monitoring of important organs during the operation is particularly important. Information such as blood perfusion, blood oxygen saturation, cardiac output, and neurophysiological conduction potential changes should be obtained in a timely fashion, which will help to reduce the risk of hypotension. In short, when applying controlled hypotension, it is necessary to choose an appropriate threshold and duration, and appropriate monitoring should be conducted during the operation to ensure the safety of the patient.

Indexed as

HypotensionHypotension, ControlledSpinal NeoplasmsHumanscomplicationcontrolled hypotensionintraoperative hemostasisintraoperative monitoringspinal metastasis

Identifiers

PMID35668701
PMCPMC9178972
OpenAlexW4282926876

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.