Evidence map›Paper›PMID 35668679›Full record

SynthesisRevista brasileira de ginecologia e obstetricia : revista da Federacao Brasileira das Sociedades de Ginecologia e Obstetricia2022

Relation between Selenium and Female Fertility: A Systematic Review.

Luiz Gustavo Lima, André Amaro Mamédio Dos Santos, Tiago Daniel Gueiber, Ricardo Zanetti Gomes, Camila Marinelli Martins, Andrielle Cristina Chaikoski

Open access · diamondAbstract readSystematic Review
In one paragraph

Synthesis in Revista brasileira de ginecologia e obstetricia : revista da Federacao Brasileira das Sociedades de Ginecologia e Obstetricia, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.1field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 11 citations in OpenAlex.

  1. Selenium-Based Nanoplatforms: An Emerging Theranostic Paradigm for Gynecological Cancers.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Review
  2. Review
  3. Article
  4. Article
  5. Selenium Content of the Gonads of the Domestic Dog (Animals : an open access journal from MDPI · 2025
    Article
  6. Review
  7. Review
  8. Selenium in Surgery.Cureus · 2024
    Review
  9. Review
  10. Review
  11. Review
  12. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Luiz Gustavo LimaDepartment of Medicine, Universidade Estadual de Ponta Grossa, Ponta Grossa, PR, Brazil.ORCID 0000-0002-3034-3202
André Amaro Mamédio Dos SantosDepartment of Medicine, Universidade Estadual de Ponta Grossa, Ponta Grossa, PR, Brazil.ORCID 0000-0003-1077-0095
Tiago Daniel GueiberDepartment of Medicine, Universidade Estadual de Ponta Grossa, Ponta Grossa, PR, Brazil.ORCID 0000-0003-1703-2298
Ricardo Zanetti GomesDepartment of Medicine, Universidade Estadual de Ponta Grossa, Ponta Grossa, PR, Brazil.ORCID 0000-0002-9651-8298
Camila Marinelli MartinsDepartment of Medicine, Universidade Estadual de Ponta Grossa, Ponta Grossa, PR, Brazil.ORCID 0000-0002-8425-5769
Andrielle Cristina ChaikoskiDepartment of Medicine, Universidade Estadual de Ponta Grossa, Ponta Grossa, PR, Brazil.ORCID 0000-0002-1253-1285
Universidade Estadual de Ponta Grossa · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo analyze the influence of selenium in female fertility. DATA SOURCE: A search was performed in the following databases: MEDLINE, Web of Science, Scopus, SciELO, LILACS, MDPI, ScienceDirect, and Europe PMC. The descriptors selected were " STUDY SELECTION: The evaluation was performed independently by two reviewers, and a third reviewer confirmed the inclusion of papers in case of divergence between the first two reviewers. Papers were selected after the title and abstract were read, and those that met the eligibility criteria had the full text read. DATA COLLECTION: The following data was extracted: author, year of publication, country, type of study, objective, method, sample size, follow-up period, patients' mean age, inclusion and exclusion criteria, and concentration of serum and capillary selenium. The data was organized in chronological order of paper publication. DATA SYNTHESIS: The number of papers identified totaled 3,800, out of which 7 were included in the systematic review. The studies indicated a positive correlation between serum selenium and antioxidant concentration in the follicular fluid, reduction in antithyroid antibodies, oocyte production and follicle number.

conclusionSelenium supplementation is promising in women with this micronutrient deficiency to promote improvement of the reproductive efficiency and prevent damage to the pregnancy. Further studies on this theme are still required.

Indexed as

SeleniumEuropeFemaleHumansOvarian FolliclePregnancySelenium

Identifiers

PMID35668679
PMCPMC9948146
OpenAlexW4281995753

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.