ArticleJournal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance2022
Imaging gravity-induced lung water redistribution with automated inline processing at 0.55 T cardiovascular magnetic resonance.
Article in Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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11 citing papers in PubMed.
- Reproducibility of T2 relaxation time mapping in a phantom and human knee articular cartilage.Magma (New York, N.Y.) · 2026Article
- Free-breathing 3D pulmonary ventilation mapping at 0.55 T using stack-of-spiral out-in bSSFP.Magnetic resonance in medicine · 2026Article
- Artificial intelligence improves detection and classification of pulmonary venous hypertension related to left ventricular diastolic dysfunction by chest radiography.Scientific reports · 2025Article
- MRI Assessment of Lung Water Density in Individuals Previously Infected With COVID-19: A Cross-Sectional Study.Journal of magnetic resonance imaging : JMRI · 2025Article
- Characterizing extravascular lung water-A dual-contrast agent extracellular volume approach by cardiovascular magnetic resonance.Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance · 2025Article
- Assessment of the Diagnostic Efficacy of Low-Field Magnetic Resonance Imaging: A Systematic Review.Diagnostics (Basel, Switzerland) · 2024Review
- Lung water density is increased in patients at risk of heart failure and is largely independent of conventional cardiovascular magnetic resonance measures.European heart journal. Imaging methods and practice · 2024Article
- Cardiac MRI at Low Field Strengths.Journal of magnetic resonance imaging : JMRI · 2024Review
- New clinical opportunities of low-field MRI: heart, lung, body, and musculoskeletal.Magma (New York, N.Y.) · 2024Review
- Dynamic lung water MRI during exercise stress.Magnetic resonance in medicine · 2023Article
- Lung parenchyma transverse relaxation rates at 0.55 T.Magnetic resonance in medicine · 2023Article
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Authors and funding
9 authors.
Funding
Abstract
backgroundQuantitative assessment of dynamic lung water accumulation is of interest to unmask latent heart failure. We develop and validate a free-breathing 3D ultrashort echo time (UTE) sequence with automated inline image processing to image changes in lung water density (LWD) using high-performance 0.55 T cardiovascular magnetic resonance (CMR).
methodsQuantitative lung water CMR was performed on 15 healthy subjects using free-breathing 3D stack-of-spirals proton density weighted UTE at 0.55 T. Inline image reconstruction and automated image processing was performed using the Gadgetron framework. A gravity-induced redistribution of LWD was provoked by sequentially acquiring images in the supine, prone, and again supine position. Quantitative validation was performed in a phantom array of vials containing mixtures of water and deuterium oxide.
resultsThe phantom experiment validated the capability of the sequence in quantifying water density (bias ± SD 4.3 ± 4.8%, intraclass correlation coefficient, ICC = 0.97). The average global LWD was comparable between imaging positions (supine 24.7 ± 3.4%, prone 22.7 ± 3.1%, second supine 25.3 ± 3.6%), with small differences between imaging phases (first supine vs prone 2.0%, p < 0.001; first supine vs second supine - 0.6%, p = 0.001; prone vs second supine - 2.7%, p < 0.001). In vivo test-retest repeatability in LWD was excellent (- 0.17 ± 0.91%, ICC = 0.97). A regional LWD redistribution was observed in all subjects when repositioning, with a predominant posterior LWD accumulation when supine, and anterior accumulation when prone (difference in anterior-posterior LWD: supine - 11.6 ± 2.7%, prone 5.5 ± 2.7%, second supine - 11.4 ± 2.9%). Global LWD maps were calculated inline within 23.2 ± 0.3 s following the image reconstruction using the automated pipeline.
conclusionsRedistribution of LWD due to gravitational forces can be depicted and quantified using a validated free-breathing 3D proton density weighted UTE sequence and inline automated image processing pipeline on a high-performance 0.55 T CMR system.
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