Evidence map›Paper›PMID 35668279›Full record

ArticleObesity surgery2022

Clinical and Economic Impact of Bariatric Surgery Post Liver Transplantation: a Nationwide, Population-Based Retrospective Study.

Andrea Chierici, Julie Bulsei, Antonio Castaldi, Nicolo' Petrucciani, Céline Drai, Anne-Sophie Schneck, Nicolas Chevalier, Eric Fontas, Antonio Iannelli

Abstract read
PubMed Publisher
In one paragraph

Article in Obesity surgery, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.6field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Key challenges of post-liver transplant weight management.World journal of transplantation · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 2 countries.

Andrea ChiericiService de Chirurgie Digestive, Centre Hospitalier d'Antibes Juan-Les-Pins, 107, Av. de Nice, 06600, Antibes, France.
Julie BulseiDepartment of Clinical Research and Innovation, Centre Hospitalier Universitaire de Nice, Université Côte D'Azur, Nice, France.
Antonio CastaldiCentre Hospitalier Universitaire de Nice - Digestive Surgery and Liver Transplantation Unit, Archet 2 Hospital, 151 Route Saint Antoine de Ginestière, BP 3079, Cedex 3, Nice, France.
Nicolo' PetruccianiDepartment of Medical and Surgical Sciences and Translational Medicine, Faculty of Medicine and Psychology, St. Andrea Hospital, Sapienza University, Rome, Italy.
Céline DraiCentre Hospitalier Universitaire de Nice - Digestive Surgery and Liver Transplantation Unit, Archet 2 Hospital, 151 Route Saint Antoine de Ginestière, BP 3079, Cedex 3, Nice, France.
Anne-Sophie SchneckCentre Hospitalier Universitaire de Guadeloupe-Digestive Surgery Unit, 97159, Pointe à Pitre, Guadeloupe.
Nicolas ChevalierUniversité Côte d'Azur, Nice, France.
Eric FontasDepartment of Clinical Research and Innovation, Centre Hospitalier Universitaire de Nice, Université Côte D'Azur, Nice, France.
Antonio IannelliDepartment of Clinical Research and Innovation, Centre Hospitalier Universitaire de Nice, Université Côte D'Azur, Nice, France. iannelli.a@chu-nice.fr.ORCID 0000-0002-1611-071X
Centre Hospitalier Universitaire de Nice · FRInserm · FRCentre Hospitalier de Bigorre · FRCentre Hospitalier Universitaire Pointe-à-Pitre · GP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposePrevalence of obesity in liver transplant recipients is increasing with the overall epidemic augmentation of severe obesity, the effects of immunosuppressive drugs, and lifestyle changes which are responsible for de novo obesity development or aggravation of pre-existing obesity. The aim of this study is to analyze the differences in overall mortality, re-hospitalization rate, and hospitalization-related costs between patients undergoing bariatric surgery after liver transplantation and patients undergoing bariatric surgery alone. MATERIALS AND

methodsTwenty patients with history of liver transplantation who underwent bariatric surgery were analyzed from the French National Hospital Discharge Database. Overall mortality, re-hospitalization rate, length of stay for bariatric procedure, and the costs of bariatric surgery hospitalization and eventual re-hospitalizations were compared to a group of 360,846 patients who underwent bariatric surgery alone from 2010 to 2019. Furthermore, a 1:1 propensity score matching analysis was conducted.

resultsPatients with a history of liver transplantation showed an increased risk of overall mortality (HR: 7.66, p = 0.0047) and increased costs of hospitalization for bariatric surgery (8250 ± 4822€ vs 5583 ± 3398€, p = 0.0005). No differences in length of stay, re-hospitalization rate, and costs were found after multivariate analysis. After propensity score matching analysis, a significant increased cost of hospitalization (8250 ± 4822€ vs 6086 ± 1813€, p = 0.0195) still resulted for the liver transplantation group.

conclusionBariatric surgery represents the best treatment for obesity and its related associated medical problems. Our study highlights an increased risk of overall all-cause mortality and increased costs of hospitalization in this population compared to patients undergoing bariatric surgery alone.

Indexed as

Bariatric SurgeryLiver TransplantationObesity, MorbidHospital MortalityHumansObesityRetrospective StudiesBariatric surgeryCostLiver transplantationMortalityObesity

Identifiers

PMID35668279
OpenAlexW4281701639

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.