ArticleNature chemistry2022
Environmental conditions drive self-organization of reaction pathways in a prebiotic reaction network.
Article in Nature chemistry, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.
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Who cites it
30 citing papers in PubMed, 91 citations in OpenAlex.
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- Comprehensive Mapping of Compositional Dynamics in the Formose Reaction Network.Angewandte Chemie (International ed. in English) · 2026Article
- Complex and Messy Prebiotic Chemistry: Obstacles and Opportunities for an RNA World.Life (Basel, Switzerland) · 2026Review
- Isolation of bacteria that catabolize abiotically synthesized tetroses via the formose reaction.Scientific reports · 2025Article
- Robotic system takes chemistry into hyperspace.Nature · 2025Article
- Sugars to Acids via Thioesters: A Computational Study.Life (Basel, Switzerland) · 2025Article
- Environmental History is Transferred via Minerals Altering Formose Reaction Pathways.Angewandte Chemie (International ed. in English) · 2025Article
- Multilayered substructures of a non-enzymatic chemical reaction network for synthesizing sugars.Communications chemistry · 2025Article
- Autocatalytic assembly of a chimeric aminoacyl-RNA synthetase ribozyme.Science advances · 2025Article
- The second wave of formose research.BBA advances · 2025Article
- Selection-diversification interplay in oligonucleotide chemical evolution.Biophysics and physicobiology · 2025Article
- Sulfur Analogs of the Core Formose Cycle: A Free Energy Map.Life (Basel, Switzerland) · 2024Article
- Exploring the programmability of autocatalytic chemical reaction networks.Nature communications · 2024Article
- Alternative Pathways in Astrobiology: Reviewing and Synthesizing Contingency and Non-Biomolecular Origins of Terrestrial and Extraterrestrial Life.Life (Basel, Switzerland) · 2024Review
- Exploring the Core Formose Cycle: Catalysis and Competition.Life (Basel, Switzerland) · 2024Article
- Article
- Emergence of a short peptide based reductase via activation of the model hydride rich cofactor.Nature communications · 2024Article
- Distilling dynamical knowledge from stochastic reaction networks.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- Chemical Information Processing by a Responsive Chemical System.Journal of the American Chemical Society · 2024Article
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The evolution of life from the prebiotic environment required a gradual process of chemical evolution towards greater molecular complexity. Elaborate prebiotically relevant synthetic routes to the building blocks of life have been established. However, it is still unclear how functional chemical systems evolved with direction using only the interaction between inherent molecular chemical reactivity and the abiotic environment. Here we demonstrate how complex systems of chemical reactions exhibit well-defined self-organization in response to varying environmental conditions. This self-organization allows the compositional complexity of the reaction products to be controlled as a function of factors such as feedstock and catalyst availability. We observe how Breslow's cycle contributes to the reaction composition by feeding C
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