Evidence map›Paper›PMID 35668110›Full record

ArticleScientific data2022

Implementation of a MS/MS database for isoquinoline alkaloids and other annonaceous metabolites.

Salemon Akpa Agnès, Timothée Okpekon, Yvette Affoué Kouadio, Adrien Jagora, Dimitri Bréard, Emmanoel V Costa, Felipe M A da Silva, Hector H F Koolen, Anne-Marie Le Ray-Richomme, Pascal Richomme and 3 more

Abstract readDataset
In one paragraph

Article in Scientific data, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Salemon Akpa AgnèsÉquipe "Chimie des Substances Naturelles" Université Paris-Saclay, CNRS, BioCIS, 5 rue J.-B. Clément, 92290, Châtenay-Malabry, France.
Timothée OkpekonLaboratoire de Constitution et Réaction de la Matière (LCRM), UFR Sciences des Structures de la Matière et Technologie, Université Félix Houphouët-Boigny, BP 582, Abidjan 22, Côte d'Ivoire.
Yvette Affoué KouadioÉquipe "Chimie des Substances Naturelles" Université Paris-Saclay, CNRS, BioCIS, 5 rue J.-B. Clément, 92290, Châtenay-Malabry, France.
Adrien JagoraÉquipe "Chimie des Substances Naturelles" Université Paris-Saclay, CNRS, BioCIS, 5 rue J.-B. Clément, 92290, Châtenay-Malabry, France.
Dimitri BréardUniv Angers, SONAS, SFR QUASAV, F-49000, Angers, France.ORCID http://orcid.org/0000-0001-6477-9592
Emmanoel V CostaDepartamento de Química, Universidade Federal do Amazonas, Av. Rodrigo Otávio 1200, 69067-005, Manaus, AM, Brazil.
Felipe M A da SilvaCentro de Apoio Multidisciplinar (CAM), Universidade Federal do Amazonas, Av. Rodrigo Otávio 1200, 69067-005, Manaus, Brazil.
Hector H F KoolenGrupo de Pesquisa em Metabolômica e Espectrometria de Massas, Universidade do Estado do Amazonas, Av. Carvalho Leal 1777, 69065-001, Manaus, Brazil.ORCID http://orcid.org/0000-0002-0181-348X
Anne-Marie Le Ray-RichommeUniv Angers, SONAS, SFR QUASAV, F-49000, Angers, France.
Pascal RichommeUniv Angers, SONAS, SFR QUASAV, F-49000, Angers, France.
Pierre ChampyÉquipe "Chimie des Substances Naturelles" Université Paris-Saclay, CNRS, BioCIS, 5 rue J.-B. Clément, 92290, Châtenay-Malabry, France.
Mehdi A BeniddirÉquipe "Chimie des Substances Naturelles" Université Paris-Saclay, CNRS, BioCIS, 5 rue J.-B. Clément, 92290, Châtenay-Malabry, France.ORCID http://orcid.org/0000-0003-2153-4290
Pierre Le PogamÉquipe "Chimie des Substances Naturelles" Université Paris-Saclay, CNRS, BioCIS, 5 rue J.-B. Clément, 92290, Châtenay-Malabry, France. pierre.le-pogam-alluard@universite-paris-saclay.fr.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This data descriptor reports on the upload to a public repository (GNPS) of the IQAMDB, IsoQuinoline and Annonaceous Metabolites Data Base, comprising 320 tandem mass spectra. This project originated from our in-house collection of isoquinolines. The diversity of compounds included in this database was further extended through the contribution of two additional laboratories involved in isoquinoline alkaloids research: University of Angers and University of Manaus. The generated MS/MS data were processed and annotated on an individual basis to promote their straightforward reuse by natural product chemists interested in either the description of new isoquinoline alkaloids or the dereplication of isoquinoline-containing samples. The interest of the current repertoire for dereplication purposes has been validated based on the molecular networking of the well-investigated plant model Annona montana against the IQAMDB-implemented GNPS.

Identifiers

PMID35668110
PMCPMC9170680

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.