Evidence map›Paper›PMID 35667739›Full record

ReviewCritical care clinics2022

Role of Acute Thrombosis in Coronavirus Disease 2019.

Derek V Gibbs, Satya S Shreenivas, Kristin M Hudock

Open access · greenAbstract readReview
In one paragraph

Review in Critical care clinics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.6field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 1 country.

Derek V GibbsDivision of General Internal Medicine, Department of Medicine, University of Cincinnati School of Medicine, 231 Albert Sabin Way, MSB 6065, Cincinnati, OH 45267, USA.
Satya S ShreenivasDivision of Cardiology, The Christ Hospital, 2139 Auburn Avenue, Cincinnati, OH 45219, USA.
Kristin M HudockDivision of Pulmonary, Critical Care & Sleep Medicine, Department of Medicine, University of Cincinnati School of Medicine, 231 Albert Sabin Way, MSB 6053, Cincinnati, OH 45267, USA; Division of Pulmonary Biology, Cincinnati Children's Hospital Medical Center, 3333 Burnet Avenue, Cincinnati, OH 45229, USA. Electronic address: Kristin.Hudock@uc.edu.
Christ Hospital · USCincinnati Children's Hospital Medical Center · USUniversity of Cincinnati · US

Funding

The NET effect: Human CF epithelial responses to NETosisK08HL124191 · NHLBI · UNIVERSITY OF CINCINNATI · PI HUDOCK, KRISTIN MARA · 2017 to 2021
$901k
NHLBI NIH HHS K08 HL124191
6 · The paper itself

Abstract

Patients with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) are prone to venous, cerebrovascular, and coronary thrombi, particularly those with severe coronavirus disease 2019 (COVID-19). The pathogenesis is multifactorial and likely involves proinflammatory cascades, development of coagulopathy, and neutrophil extracellular traps, although further investigations are needed. Elevated levels of D-dimers are common in patients with COVID-19 and cannot be used in isolation to predict venous thromboembolism in people with SARS-CoV-2. If given early in hospital admission, therapeutic-dose heparin improves clinical outcomes in patients with moderate COVID-19. To date, antithrombotics have not improved outcomes in patients with severe COVID-19.

Indexed as

Blood Coagulation DisordersCOVID-19ThrombosisAnticoagulantsHeparinHumansSARS-CoV-2AnticoagulantsHeparinAnticoagulationCoronary thrombusCOVIDD-dimerNETsThrombosis

Identifiers

PMID35667739
PMCPMC8947965
OpenAlexW4220914203

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.