Evidence map›Paper›PMID 35667650›Full record

ArticleACS chemical biology2022

Vacuole-Specific Lipid Release for Tracking Intracellular Lipid Metabolism and Transport in

Vladimir Girik, Suihan Feng, Hanaa Hariri, W Mike Henne, Howard Riezman

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in ACS chemical biology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
2.1field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 19 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Lysosome-targeted multifunctional lipid probes reveal the sterol transporter NPC1 as a sphingosine interactor.Proceedings of the National Academy of Sciences of the United States of America · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Vladimir GirikDepartment of Biochemistry, University of Geneva, Geneva 1205, Switzerland.ORCID 0000-0003-1649-7587
Suihan FengDepartment of Biochemistry, University of Geneva, Geneva 1205, Switzerland.ORCID 0000-0002-9205-0050
Hanaa HaririDepartment of Cell Biology, UT Southwestern Medical Center, Dallas, Texas 75390-9039 United States.
W Mike HenneDepartment of Cell Biology, UT Southwestern Medical Center, Dallas, Texas 75390-9039 United States.
Howard RiezmanDepartment of Biochemistry, University of Geneva, Geneva 1205, Switzerland.ORCID 0000-0003-4680-9422
University of Geneva · CHSouthwestern Medical Center · US

Funding

Spatial determinants in lipid metabolic organization at the sub-organelle levelR35GM119768 · NIGMS · UT SOUTHWESTERN MEDICAL CENTER · PI Mike Henne · 2016 to 2026
$4.1M
Mechanisms of lipid droplet organization and functional diversificationR01DK126887 · NIDDK · UT SOUTHWESTERN MEDICAL CENTER · PI Mike Henne, sarah huen · 2021 to 2026
$2.4M
NIDDK NIH HHS R01 DK126887NIGMS NIH HHS R35 GM119768
6 · The paper itself

Abstract

Lipid metabolism is spatiotemporally regulated within cells, yet intervention into lipid functions at subcellular resolution remains difficult. Here, we report a method that enables site-specific release of sphingolipids and cholesterol inside the vacuole in

Indexed as

Saccharomyces cerevisiaeSaccharomyces cerevisiae ProteinsCholesterolIntermediate Filament ProteinsLipid MetabolismSphingolipidsVacuolesCholesterolIntermediate Filament ProteinsMDM1 protein, S cerevisiaeSaccharomyces cerevisiae ProteinsSphingolipids

Identifiers

PMID35667650
PMCPMC9207805
OpenAlexW4281674683

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.