Evidence map›Paper›PMID 35667618›Full record

ArticleJournal of AAPOS : the official publication of the American Association for Pediatric Ophthalmology and Strabismus2022

Semi-automated vessel analysis of en face posterior pole vessel maps generated from optical coherence tomography for diagnosis of plus or pre-plus disease.

Kai R Seely, Marguerite C Weinert, Gloria J Hong, Weiliang Wang, Sara Grace, Sharon F Freedman, Cynthia A Toth, S Grace Prakalapakorn

Registry-linked trialOpen access · greenAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of AAPOS : the official publication of the American Association for Pediatric Ophthalmology and Strabismus, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02887157 (Analyzing Retinal Microanatomy in Retinopathy of Prematurity to Improve Care), which is not on this map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.3field-weighted citation impact, top 46% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02887157 completednot on this map

Analyzing Retinal Microanatomy in Retinopathy of Prematurity to Improve Care (BabySTEPS)

TypeobservationalSponsorDuke UniversityRan2016 to 2021Enrolled191ConditionsRetinopathy of Prematurity, Neurodevelopmental Disorders, Macular EdemaArmsSwept Source OCT, Magnetic Resonance Imaging, Scavenged blood collection
3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Kai R SeelyDepartment of Ophthalmology, Duke University, Durham, North Carolina.
Marguerite C WeinertMassachusetts Eye and Ear, Boston, Massachusetts; Department of Ophthalmology, Harvard School of Medicine, Boston, Massachusetts.
Gloria J HongDepartment of Ophthalmology, Duke University, Durham, North Carolina.
Weiliang WangDuke-National University of Singapore Medical School, Singapore.
Sara GraceDepartment of Ophthalmology, Duke University, Durham, North Carolina.
Sharon F FreedmanDepartment of Ophthalmology, Duke University, Durham, North Carolina; Department of Pediatrics, Duke University, Durham, North Carolina.
Cynthia A TothDepartment of Ophthalmology, Duke University, Durham, North Carolina; Department of Biomedical Engineering, Duke University, Durham, North Carolina.
S Grace PrakalapakornDepartment of Ophthalmology, Duke University, Durham, North Carolina; Department of Pediatrics, Duke University, Durham, North Carolina. Electronic address: grace.prakalapakorn@duke.edu.
Duke University · USMassachusetts Eye and Ear Infirmary · USNational University of Singapore · SG

Funding

Analyzing Retinal Microanatomy in Retinopathy of Prematurity to Improve CareR01EY025009 · NEI · DUKE UNIVERSITY · PI Xi Chen, CYNTHIA ANN TOTH · 2016 to 2026
$6.6M
NRSA Training CoreTL1TR002555 · NCATS · DUKE UNIVERSITY · PI EDELMAN, DAVID · 2018 to 2022
$3.7M
NCATS NIH HHS TL1 TR002555NEI NIH HHS R01 EY025009
6 · The paper itself

Abstract

En face retinal vessel maps generated from bedside optical coherence tomography (OCT) can show posterior pole vascular tortuosity and dilation (ie, plus/pre-plus disease). In this proof-of-concept study, we found that ROPtool could trace OCT-generated retinal vessel maps with high reliability and accuracy for detecting plus or pre-plus disease.

Indexed as

Retinopathy of PrematurityTomography, Optical CoherenceDiagnosis, Computer-AssistedHumansInfant, NewbornReproducibility of ResultsRetinal Vessels

Identifiers

PMID35667618
PMCPMC9588519
OpenAlexW4281716707

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.