Evidence map›Paper›PMID 35667121›Full record

ArticleThe Analyst2022

Intracellular calcium dynamics of lymphatic endothelial and muscle cells co-cultured in a Lymphangion-Chip under pulsatile flow.

Amirali Selahi, Sanjukta Chakraborty, Mariappan Muthuchamy, David C Zawieja, Abhishek Jain

Open access · greenAbstract read
In one paragraph

Article in The Analyst, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.0field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 12 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Article
  5. Understanding the Lymphatic System: Tissue-on-Chip Modeling.Annual review of biomedical engineering · 2025
    Review
  6. Periodic Flows in Microfluidics.Small (Weinheim an der Bergstrasse, Germany) · 2024
    Review
  7. Review
  8. Review
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Amirali SelahiDepartment of Biomedical Engineering, College of Engineering, Texas A&M University, College Station, TX, USA. a.jain@tamu.edu.ORCID http://orcid.org/0000-0002-5887-4283
Sanjukta ChakrabortyDepartment of Medical Physiology, College of Medicine, Texas A&M Health Science Center, Bryan, TX, USA.
Mariappan MuthuchamyDepartment of Medical Physiology, College of Medicine, Texas A&M Health Science Center, Bryan, TX, USA.
David C ZawiejaDepartment of Medical Physiology, College of Medicine, Texas A&M Health Science Center, Bryan, TX, USA.
Abhishek JainDepartment of Biomedical Engineering, College of Engineering, Texas A&M University, College Station, TX, USA. a.jain@tamu.edu.ORCID http://orcid.org/0000-0003-2235-5139
Texas A&M Health Science Center · USTexas A&M University · US

Funding

Determinants of COVID19-induced venous thrombosis and targeted therapy assessed with bioengineered vein-chipR01HL157790 · NHLBI · BOSTON UNIVERSITY MEDICAL CAMPUS · PI CONNOR, JOHN H, COOKE, JOHN P · 2021 to 2024
$2.8M
An artery-on-a-chip system containing blood outgrowth endothelium as a model of vaso-occlusion and drug testing in sickle cell diseaseR21EB025945 · NIBIB · TEXAS ENGINEERING EXPERIMENT STATION · PI JAIN, ABHISHEK · 2018 to 2020
$581k
NHLBI NIH HHS R01 HL157790NIBIB NIH HHS R21 EB025945
6 · The paper itself

Abstract

The lymphatic vascular function is regulated by pulsatile shear stresses through signaling mediated by intracellular calcium [Ca

Indexed as

CalciumEndothelial CellsCalcium SignalingCoculture TechniquesMechanotransduction, CellularMuscle CellsPulsatile FlowCalcium

Identifiers

PMID35667121
PMCPMC9512566
OpenAlexW4282914973

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.