Evidence map›Paper›PMID 35667068›Full record

ArticleAnnals of internal medicine2022

In patients with COVID-19 at risk for severe disease, nirmatrelvir + ritonavir reduced hospitalization or death.

Athanasios Vassilopoulos, Eleftherios Mylonakis

Abstract readComment
PubMed Publisher
In one paragraph

Article in Annals of internal medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Nirmatrelvir combined with ritonavir for preventing and treating COVID-19.The Cochrane database of systematic reviews · 2023
    Pooled it
  2. Article
  3. Observational
  4. Review
  5. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Athanasios VassilopoulosRhode Island Hospital and The Miriam Hospital, Alpert Medical School of Brown University, Providence, Rhode Island, USA (A.V., E.M.).
Eleftherios MylonakisRhode Island Hospital and The Miriam Hospital, Alpert Medical School of Brown University, Providence, Rhode Island, USA (A.V., E.M.).

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

source citationHammond J, Leister-Tebbe H, Gardner A, et al.

Indexed as

COVID-19 Drug TreatmentAdultHospitalizationHumansRitonavirRitonavir

Identifiers

PMID35667068

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.