Evidence map›Paper›PMID 35666955›Full record

ArticleeLife2022

Species-specific sensitivity to TGFβ signaling and changes to the Mmp13 promoter underlie avian jaw development and evolution.

Spenser S Smith, Daniel Chu, Tiange Qu, Jessye A Aggleton, Richard A Schneider

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in eLife, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.4field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Craniofacial developmental biology in the single-cell era.Development (Cambridge, England) · 2023
    Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Spenser S SmithDepartment of Orthopaedic Surgery, University of California, San Francisco, San Francisco, United States.ORCID 0000-0002-3984-3174
Daniel ChuDepartment of Orthopaedic Surgery, University of California, San Francisco, San Francisco, United States.ORCID 0000-0003-3697-8003
Tiange QuDepartment of Orthopaedic Surgery, University of California, San Francisco, San Francisco, United States.
Jessye A AggletonDepartment of Orthopaedic Surgery, University of California, San Francisco, San Francisco, United States.
Richard A SchneiderDepartment of Orthopaedic Surgery, University of California, San Francisco, San Francisco, United States.ORCID 0000-0002-2626-3111
University of California, San Francisco · US

Funding

TEMPORAL REGULATION OF CRANIAL SKELETOGENESISR01DE016402 · NIDCR · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI RICHARD A SCHNEIDER · 2004 to 2026
$8.2M
Skeletal Biology and Biomechanics (SBB) CoreP30AR075055 · NIAMS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Wenhan Chang · 2019 to 2026
$7.1M
UCSF Core Center for Musculoskeletal Biology and MedicineP30AR066262 · NIAMS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI LOTZ, JEFFREY C. · 2014 to 2018
$3.0M
Mechanisms of Secondary Cartilage Induction and Maintenance in the JawR01DE025668 · NIDCR · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI SCHNEIDER, RICHARD A · 2016 to 2020
$2.0M
Macro Confocal Microscope System for Large-Scale Imaging in Basic and Translational BiologyS10OD021664 · OD · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI SCHNEIDER, RICHARD A · 2016 to 2016
$377k
The Role of TGF-Beta Signaling in Neural Crest-Mediated Jaw Bone RemodelingF32DE027283 · NIDCR · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI SMITH, SPENSER SCOTT · 2018 to 2020
$194k
NIAMS NIH HHS P30 AR066262NIAMS NIH HHS P30 AR075055NIDCR NIH HHS F32 DE027283NIDCR NIH HHS R01 DE016402NIDCR NIH HHS R01 DE025668NIH HHS S10 OD021664Wellcome Trust
6 · The paper itself

Abstract

Precise developmental control of jaw length is critical for survival, but underlying molecular mechanisms remain poorly understood. The jaw skeleton arises from neural crest mesenchyme (NCM), and we previously demonstrated that these progenitor cells express more bone-resorbing enzymes including

Indexed as

Bone ResorptionTransforming Growth Factor betaAnimalsCore Binding Factor Alpha 1 SubunitDucksJawMatrix Metalloproteinase 13Neural CrestQuailCore Binding Factor Alpha 1 SubunitMatrix Metalloproteinase 13Transforming Growth Factor betaavian jaw skeletonchick embryoschickendevelopmental biologyduck embryosevolutionary developmental biologyMmp13 promoterquail embryosRunx2TGFβ signalingtranscriptional regulation

Identifiers

PMID35666955
PMCPMC9246370
OpenAlexW4281614183

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.