Evidence map›Paper›PMID 35666572›Full record

ArticleJournal of the American Chemical Society2022

1-Deazaguanosine-Modified RNA: The Missing Piece for Functional RNA Atomic Mutagenesis.

Raphael Bereiter, Eva Renard, Kathrin Breuker, Christoph Kreutz, Eric Ennifar, Ronald Micura

Open access · hybridAbstract read
In one paragraph

Article in Journal of the American Chemical Society, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 18 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Calculated pThe journal of physical chemistry. A · 2023
    Article
  6. Scaling Catalytic Contributions of Small Self-Cleaving Ribozymes.Angewandte Chemie (International ed. in English) · 2022
    Article
  7. Scaling Catalytic Contributions of Small Self-Cleaving Ribozymes.Angewandte Chemie (Weinheim an der Bergstrasse, Germany) · 2022
    Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Raphael BereiterInstitute of Organic Chemistry and Center for Molecular Biosciences, University of Innsbruck, Innrain 80-82, Innsbruck 6020, Austria.
Eva RenardArchitecture et Réactivité de l'ARN - CNRS UPR 9002, Université de Strasbourg, Institut de Biologie Moléculaire et Cellulaire, 2 Allée Conrad Roentgen, Strasbourg 67084, France.
Kathrin BreukerInstitute of Organic Chemistry and Center for Molecular Biosciences, University of Innsbruck, Innrain 80-82, Innsbruck 6020, Austria.
Christoph KreutzInstitute of Organic Chemistry and Center for Molecular Biosciences, University of Innsbruck, Innrain 80-82, Innsbruck 6020, Austria.ORCID 0000-0002-7018-9326
Eric EnnifarArchitecture et Réactivité de l'ARN - CNRS UPR 9002, Université de Strasbourg, Institut de Biologie Moléculaire et Cellulaire, 2 Allée Conrad Roentgen, Strasbourg 67084, France.
Ronald MicuraInstitute of Organic Chemistry and Center for Molecular Biosciences, University of Innsbruck, Innrain 80-82, Innsbruck 6020, Austria.ORCID 0000-0003-2661-6105
Universität Innsbruck · ATCentre National de la Recherche Scientifique · FR

Funding

Austrian Science Fund FWF P 31691Austrian Science Fund FWF P 34370
6 · The paper itself

Abstract

Atomic mutagenesis is the key to advance our understanding of RNA recognition and RNA catalysis. To this end, deazanucleosides are utilized to evaluate the participation of specific atoms in these processes. One of the remaining challenges is access to RNA-containing 1-deazaguanosine (c

Indexed as

RNARNA, CatalyticBase PairingGuanineMutagenesisNucleic Acid ConformationGuanineRNARNA, Catalytic

Identifiers

PMID35666572
PMCPMC9204769
OpenAlexW4281640226

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.