Evidence map›Paper›PMID 35666351›Full record

Observational studyIrish journal of medical science2023

The relationship between infarct volume and high sensitivity troponin I level in patients diagnosed with ischemic stroke.

Arif Aksu, Akkan Avci, Sadiye Yolcu, Adem Kaya, Begum Seyda Avci, Mustafa Oguz Tugcan, Ozan Demir, Okan Dilek, Fatih Necip Arici, Huseyin Ali Ozturk and 2 more

Abstract readObservational StudyMulticenter Study
PubMed Publisher
In one paragraph

Observational study in Irish journal of medical science, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Arif AksuDepartment of Emergency Medicine, Adana City Research and Training Hospital, Health Science University, 01060, Adana, Turkey.ORCID http://orcid.org/0000-0001-8987-0640
Akkan AvciDepartment of Emergency Medicine, Adana City Research and Training Hospital, Health Science University, 01060, Adana, Turkey. drakkanavci@gmail.com.ORCID http://orcid.org/0000-0002-4627-0909
Sadiye YolcuDepartment of Emergency Medicine, Adana City Research and Training Hospital, Health Science University, 01060, Adana, Turkey.ORCID http://orcid.org/0000-0003-3323-9213
Adem KayaDepartment of Emergency Medicine, Adana City Research and Training Hospital, Health Science University, 01060, Adana, Turkey.ORCID http://orcid.org/0000-0001-9529-1354
Begum Seyda AvciDepartment of Internal Medicine, Adana City Research and Training Hospital, Health Science University, Adana, Turkey.ORCID http://orcid.org/0000-0001-6149-9341
Mustafa Oguz TugcanDepartment of Emergency Medicine, Adana City Research and Training Hospital, Health Science University, 01060, Adana, Turkey.ORCID http://orcid.org/0000-0002-1200-9198
Ozan DemirDepartment of Emergency Medicine, Adana City Research and Training Hospital, Health Science University, 01060, Adana, Turkey.ORCID http://orcid.org/0000-0001-5713-0496
Okan DilekDepartment of Radiology, Ersin Aslan Education and Research Hospital, Gaziantep, Turkey.ORCID http://orcid.org/0000-0002-2144-2460
Fatih Necip AriciDepartment of Internal Medicine, Adana City Research and Training Hospital, Health Science University, Adana, Turkey.ORCID http://orcid.org/0000-0002-1160-2125
Huseyin Ali OzturkDepartment of Internal Medicine, Adana City Research and Training Hospital, Health Science University, Adana, Turkey.ORCID http://orcid.org/0000-0001-5713-004X
Hilmi Erdem SumbulDepartment of Internal Medicine, Adana City Research and Training Hospital, Health Science University, Adana, Turkey.ORCID http://orcid.org/0000-0002-7192-0280
Ferhat IcmeDepartment of Emergency Medicine, Ankara City Hospital, Ankara, Turkey.ORCID http://orcid.org/0000-0001-5180-7152

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundVarious biomarkers and clinical variables are used to determine the probability risk, diagnosis, and the prognosis of acute ischemic stroke, but effective markers are still warranted.

aimWe aimed to determine the effectiveness of Hs-cTnI levels to predict the prognosis of AIS.

methodsThis study was planned as a retrospective observational study. Patients with available data and over 18 years old were included in the study. Diffusion magnetic resonance images were evaluated by a senior radiologist and the infarct size was calculated.

resultsWe included 110 (54.2%) males and 93 (45.8%) females; a total of 203 patients with a mean age of 68.9 were included in the present study. Patients were divided into two groups according to the cut-off level of Hs-troponin-I (group I: lower than 8.5 mg/dL; group 2: higher than 8.5 mg/dL). These two groups were compared for mortality and infarct volume. Infarct volume and the mortality ratio of the group 2 was significantly higher [p = 0.041, U = 4294.5, LV = 6.5 (IQR = 1.8-25.4)].

conclusionsHs-troponin I may be an effective biomarker in predicting the prognosis of patients with acute ischemic stroke. Multicenter comprehensive prospective studies are warranted to obtain stronger results.

Indexed as

Ischemic StrokeStrokeAdolescentAgedBiomarkersFemaleHumansInfarctionMalePrognosisTroponin ITroponin TBiomarkersTroponin ITroponin TAcute ischemic strokeEmergencyGKSHigh sensitive troponin IMortality

Identifiers

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.