ArticleAnnals of intensive care2022
Organ donation after out-of-hospital cardiac arrest: a population-based study of data from the Paris Sudden Death Expertise Center.
Article in Annals of intensive care, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.
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Who cites it
9 citing papers in PubMed, 1 synthesis or guideline pooled it, 12 citations in OpenAlex.
- Part 4: Systems of Care: 2025 American Heart Association Guidelines for Cardiopulmonary Resuscitation and Emergency Cardiovascular Care.Circulation · 2025Guideline
- Documenting graft outcome to substantiate the organ-donation rationale after out-of-hospital cardiac arrest due to aneurysmal subarachnoid haemorrhage.Critical care (London, England) · 2026Article
- Multimodal Prediction of Progression Toward Brain Death After Out-of-Hospital Cardiac Arrest.Journal of clinical medicine · 2026Article
- The Effect of an Educational Intervention Program on Allied Health Students' Knowledge and Attitudes Regarding Organ Donation and Transplantation.Nursing reports (Pavia, Italy) · 2026Article
- Out-of-Hospital Cardiac Arrest Patients: Different Donor Pathways for an Existing Donor Pool Still Underestimated-Perspective.Journal of clinical medicine · 2025Article
- Ten Steps Toward Improving In-Hospital Cardiac Arrest Quality of Care and Outcomes.Resuscitation · 2023Article
- Ten Steps Toward Improving In-Hospital Cardiac Arrest Quality of Care and Outcomes.Circulation. Cardiovascular quality and outcomes · 2023Review
- Anesthetic Considerations of Organ Procurement After Brain and Cardiac Death: A Narrative Review.Cureus · 2023Review
- Uncontrolled Donation Potential After Circulatory Death in Slovenia Could Lead to More Organ Donations: Extrapolation of SiOHCA Study Data.Inquiry : a journal of medical care organization, provision and financingArticle
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Authors and funding
13 authors at 9 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundOrgan shortage is a major public health issue, and patients who die after out-of-hospital cardiac arrest (OHCA) could be a valuable source of organs. Here, our objective was to identify factors associated with organ donation after brain death complicating OHCA, in unselected patients entered into a comprehensive real-life registry covering a well-defined geographic area.
methodsWe prospectively analyzed consecutive adults with OHCA who were successfully resuscitated, but died in intensive care units in the Paris region in 2011-2018. The primary outcome was organ donation after brain death. Independent risk factors were identified using logistic regression analysis. One-year graft survival was assessed using Cox and log-rank tests.
resultsOf the 3061 included patients, 136 (4.4%) became organ donors after brain death, i.e., 28% of the patients with brain death. An interaction between admission pH and post-resuscitation shock was identified. By multivariate analysis, in patients with post-resuscitation shock, factors associated with organ donation were neurological cause of OHCA (odds ratio [OR], 14.5 [7.6-27.4], P < 0.001), higher pH (OR/0.1 increase, 1.3 [1.1-1.6], P < 0.001); older age was negatively associated with donation (OR/10-year increase, 0.7 [0.6-0.8], P < 0.001). In patients without post-resuscitation shock, the factor associated with donation was neurological cause of OHCA (OR, 6.9 [3.0-15.9], P < 0.001); higher pH (OR/0.1 increase, 0.8 [0.7-1.0], P = 0.04) and OHCA at home (OR, 0.4 [0.2-0.7], P = 0.006) were negatively associated with organ donation. One-year graft survival did not differ according to Utstein characteristics of the donor.
conclusions4% of patients who died in ICU after OHCA led to organ donation. Patients with OHCA constitute a valuable source of donated organs, and special attention should be paid to young patients with OHCA of neurological cause.
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