Evidence map›Paper›PMID 35666231›Full record

ArticleJournal of child and adolescent psychopharmacology2022

Dose Proportionality and Steady-State Pharmacokinetics of Serdexmethylphenidate/Dexmethylphenidate, a Novel Prodrug Combination to Treat Attention-Deficit/Hyperactivity Disorder.

Rene Braeckman, Sven Guenther, Travis C Mickle, Andrew C Barrett, Adam Smith, Charles Oh

Open access · hybridAbstract read
In one paragraph

Article in Journal of child and adolescent psychopharmacology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
2.4field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 16 citations in OpenAlex.

  1. Review
  2. Article
  3. Current knowledge on the pathophysiology of idiopathic hypersomnia and potential mechanisms of action for low-sodium oxybate treatment.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2025
    Review
  4. Review
  5. Article
  6. Review
  7. Review
  8. Advancements in Drug Repurposing: Examples in Psychiatric Medications.International journal of molecular sciences · 2023
    Article
  9. Review
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Rene BraeckmanKemPharm, Inc., Celebration, Florida, USA.
Sven GuentherKemPharm, Inc., Celebration, Florida, USA.
Travis C MickleKemPharm, Inc., Celebration, Florida, USA.
Andrew C BarrettKemPharm, Inc., Celebration, Florida, USA.
Adam SmithKemPharm, Inc., Celebration, Florida, USA.
Charles OhCorium, Inc., Grand Rapids, Michigan, USA.
KemPharm (United States) · USLakeland Library Cooperative · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Attention Deficit Disorder with HyperactivityCentral Nervous System StimulantsDexmethylphenidate HydrochlorideMethylphenidateProdrugsArea Under CurveBiological AvailabilityCross-Over StudiesDelayed-Action PreparationsHumansCentral Nervous System StimulantsDelayed-Action PreparationsDexmethylphenidate HydrochlorideMethylphenidateProdrugsattention-deficit/hyperactivity disordermethylphenidatepharmacokineticsserdexmethylphenidatestimulant

Identifiers

PMID35666231
PMCPMC9245728
OpenAlexW4281789916

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.