ArticleANZ journal of surgery2022
Recurrence patterns predict survival after resection of colorectal liver metastases.
Article in ANZ journal of surgery, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
19 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Prognostic factors associated with early recurrence following liver resection for colorectal liver metastases: a systematic review and meta-analysis.BMC cancer · 2024Pooled it
- Recurrence patterns stratify post-progression survival after early recurrence of colorectal liver metastases following hepatectomy: a single-center retrospective study.World journal of surgical oncology · 2026Article
- CT radiomics for survival risk stratification in resectable colorectal liver metastases: a multi-centre study.Scientific reports · 2026Article
- The Clinical Relevance of Indeterminate Pulmonary Nodules in Patients Amenable to Local Treatment of Colorectal Liver Metastases.Annals of surgery open : perspectives of surgical history, education, and clinical approaches · 2026Article
- Gender differences in the plasma profiles of proprotein convertase subtilisin/kexin-type 9 (PCSK9), soluble low-density lipoprotein receptor (sLDLR), total cholesterol, and triglycerides in patients with colorectal cancer liver metastases: diagnostic and prognostic implications.Lipids in health and disease · 2026Article
- Presurgical levels of circulating tumour DNA in patients with resectable chemotherapy-naïve colorectal liver metastases: association with multiorgan recurrence and survival in the MIRACLE cohort.The British journal of surgery · 2026Article
- Dormancy in Metastatic Colorectal Cancer: Tissue Engineering Opportunities forTissue engineering. Part B, Reviews · 2026Review
- Decellularized Extracellular Matrix Scaffolds to Engineer the Dormant Landscape of Microscopic Colorectal Cancer Liver Metastasis.Advanced healthcare materials · 2026Article
- Early unresectable relapse after hepatic resection for colorectal liver metastases: a focus on time to surgical failure.Updates in surgery · 2026Article
- Hepatic Recurrence Rate Based on Extent of Adjuvant Floxuridine Exposure After Resection of Colorectal Liver Metastases.Annals of surgical oncology · 2026Article
- Data-driven identification and semi-automated quantification of molecular targets for tumour-imaging of colorectal liver metastases and primary colorectal tumours.EJNMMI research · 2025Article
- Proteomic Landscape of Colorectal Cancer Derived Liver Metastasis Reveals Three Distinct Phenotypes With Specific Signaling and Enhanced Survival.Molecular & cellular proteomics : MCP · 2025Article
- A CT-based radiomics tumor quality and quantity model to predict early recurrence after radical surgery for colorectal liver metastases.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2025Article
- Predicting the recurrence risk of liver metastasis from colorectal cancer: a study based on preoperative CT intratumoral and peritumoral radiomics features.Frontiers in oncology · 2025Article
- Article
- Prognostic potential of whole exome sequencing in the clinical management of metachronous colorectal cancer liver metastases.Cancer cell international · 2023Article
- Article
- Current Challenges in Defining Futile Liver Resection and Predicting Early Recurrence After Curative-Intent Treatment for Colorectal Liver Metastases.Annals of surgical oncology · 2023Article
- Case Report: Long-term survival of a patient with advanced rectal cancer and multiple pelvic recurrences after seven surgeries.Frontiers in oncology · 2023Article
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Authors and funding
7 authors.
Funding
Abstract
backgroundEffective treatment of colorectal liver metastases (CRLM) is challenging because recurrence occurs in many patients after curative-intent resection. This study evaluates the recurrence patterns after resection of CRLM and its association with survival.
methodsA retrospective review of prospectively collected data of patients with CRLM managed with curative-intent resection from January 2007 to December 2017 was performed. The main outcomes and measures were the timing of recurrence, initial sites of recurrence, overall survival and recurrence-free survival. Early recurrence was defined as the detection of any organ recurrence ≤6 months from resection of CRLM.
resultsA cohort of 194 patients was included for analysis. After a median follow-up of 85.3 months, 145 patients (74.7%) were diagnosed with recurrence. The median overall survival was 67.6 months (95% CI 50.4-80.2) and the 5-year overall survival was 54.1%. After initial recurrence was detected, the median survival was 28.9 months (95% CI 23.6-37.8) months and the 5-year overall survival was 28.8%. Early recurrence occurred in 58 patients (29.9%). Initial recurrence patterns included: liver only in 53 patients (36.5%), multiple sites in 48 patients (33.1%), lung only in 30 patients (20.7%), and other single extrahepatic sites in 14 patients (9.6%). Early recurrence and initial multi-site recurrence were independent predictors of worse overall survival for patients who develop recurrence after resection of CLRM.
conclusionThe timing and initial sites of recurrence are prognostic factors in determining survival after curative-intent resection of CRLM.
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