Evidence map›Paper›PMID 35666116›Full record

ArticleActa bio-medica : Atenei Parmensis2022

Clinical and Epidemiological Features of Pediatric Patients with COVID-19 in a Tertiary Pediatric Hospital.

Maria De Filippo, Paola Magri, Grazia Bossi, Ilaria Brambilla, Riccardo Castagnoli, Amelia Mascolo, Martina Votto, Amelia Licari, Gian Luigi Marseglia

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Article in Acta bio-medica : Atenei Parmensis, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

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0cells of the map it votes in
4citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

9 authors.

Maria De Filippo. maria_defilippo@hotmail.it.
Paola Magri. paola.magri01@universitadipavia.it.
Grazia Bossi. g.bossi@smatteo.pv.it.
Ilaria Brambilla. i.brambilla@smatteo.pv.it.
Riccardo Castagnoli. riccardo.castagnoli@yahoo.it.
Amelia Mascolo. a.mascolo@smatteo.pv.it.
Martina Votto. martina.votto@unipv.it.
Amelia Licari. amelia.licari@unipv.it.
Gian Luigi Marseglia. gl.marseglia@smatteo.pv.it.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCoronavirus disease 2019 (COVID-19) affects people of any age with high mortality and morbidity in adults older than 65 years. Reports on pediatric cases highlighted those children generally develop milder symptoms than adults or are asymptomatic. We aimed to assess the epidemiological and clinical data of children and adolescents with SARS-CoV-2 infection to improve pediatric COVID-19.

methodsWe retrospectively analyzed clinical and epidemiological features of patients with SARS-CoV-2 infection hospitalized at the Pediatric Hospital of Pavia, Italy, between February 1, 2020, to April 30, 2021.

results71 patients aged 0-16 years were included; 33 (46%) females and 38 (54 %) males. Thirty-three (46%) patients had comorbidities, such as obesity and hematological diseases. Thirty-one children (44%) were exposed to COVID-19-positive household members. Nine (12.7 %) patients were asymptomatic, whereas 57 (80.3%) had a mild-moderate disease. Only five (7%) showed a severe or critical disease, and two patients required ICU admission. The most frequent symptoms were fever (76%), loss of appetite (26%), gastrointestinal symptoms (19%), and cough (19%). Chest X-ray was performed in 42 patients showing lung abnormalities in more than half of symptomatic patients. The most common laboratory features were lymphopenia and eosinopenia associated with high levels of inflammation markers.

conclusionsThis study confirmed that COVID-19 has a mild course in children compared to adults. Most of the enrolled children were asymptomatic or had a mild-moderate disease. Patients with comorbidities were more prone to develop clinical complications.

Indexed as

COVID-19AdolescentAdultChildFemaleHospitals, PediatricHumansMaleRetrospective StudiesSARS-CoV-2Tertiary Care Centers

Identifiers

PMID35666116
PMCPMC9494185

What OpenQuestion holds

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LicenceCC BY-NC-SA
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.